Since 1937, the Jane Coffin Childs Memorial Fund has been offering highly-qualified scientists the opportunity to pursue research into the causes and origins of cancer.Apply Now
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Dr. Angelika Amon, HHMI Investigator and MIT professor, joins the BSA this year. “The [...]Read More
I am interested in cellular transport, or in other words, how things, like organelles, mRNA, and viruses are shuttled around the cell. In the Reck-Peterson lab, we study the microtubule-associated motor protein, dynein. Dynein is a large, muti-subunit complex that walks towards the center of the cell along microtubule tracks. I am particularly interested in understanding how other proteins, referred to as dynein-adaptors, regulate dynein function and specificity for cellular cargo. In our lab, we take a two-pronged approach to understanding dynein biology. First, we use techniques like single molecule-fluorescence microscopy and electron microscopy to study dynein function on a mechanistic level. Secondly, we use mass spectrometry to conduct proteomic screens to identify novel proteins that interact with dynein.