

Harvard University
Sponsor: Xiaowei ZhuangA single-molecule study of reverse transcriptase


Massachusetts Institute of Technology
Sponsor: Sheldon PenmanNucleic acid antagonists at the subcellular level


Stanford University
Sponsor: Karla KirkegaardDetermining how diverse RNA viruses manipulate the autophagy pathway


Iowa State University
Sponsor: Jonathan WendelExpression of genecin in allopolyploids


University of California, Irvine
Sponsor: PJ Bryant and Howard Schneiderman

Rockefeller University
Sponsor: Charles RiceEntering the unknown: How do viruses transition to new hosts?


Salk Institute for Biological Studies
Sponsor: Andrew DillinThe genetics of dietary restriction


University of California, San Francisco
Sponsor: Geeta NarlikarInvestigating the core mechanisms of heterochromatin formation


Johns Hopkins University
Sponsor: Paul Ts'OPhysicochemical properties of ribopolymers


University of California, San Francisco
Sponsor: Wendell LimSynthetic control of immune cell traffiking


University of Colorado, Boulder
Sponsor: Larry GoldInteractions between nucleic acid ligands and HIV-1 proteins.


Stanford University
Sponsor: Ronald W. DavisOrganization and expression of d. discoideum genome

University of California, Berkeley
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University of California, Berkeley
Sponsor: John KuriyanSubstrate docking and ubiquitylation in the E3 ligase Cbl , with John Kuriyan


University of California, Berkeley
Sponsor: Raymond E. KellerCell interactions patterning the vertefrate embryo


University of California, Berkeley
Sponsor: Daniel MaziaEffect of oxygen-lack on mitosis


Cold Spring Harbor Laboratory
Sponsor: Raymond GestelandControl of protein synthesis in a cell-free system


Dana-Farber Cancer Institute
Sponsor: Pamela A SilverMovement of hnRNP proteins in and out of the nucleus

University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center
Sponsor: Michael S BrownPurification of farnesyl-systein protease


New York University
Sponsor: David D SabatiniTargeting of cloned beta glucuronidase to lysosomes


Harvard University
Sponsor: Richard M LosickIdentification of cell division genes in Epulopiscium


Broad Institute
Sponsor: David LiuGenome editing with single nucleotide precision


Massachusetts General Hospital
Sponsor: Konrad HochedlingerDifferentiation hierarchy and reprogramming potential in hematopoietic cells


California Institute of Technology
Sponsor: Raymond J DeshaiesBiochemical analysis of anaphase promoting complex


Columbia University
Sponsor: Eric GouauxSimultaneous measurement of AMPA receptor structure and function


Stanford University
Sponsor: Paul BergIsoleucyl transfer ribonucleic acid synthetase


California Institute of Technology
Sponsor: Pamela BjorkmanStructure and function of the NKp30 killer receptor


California Institute of Technology
Sponsor: Michael ElowitzDynamics of cell state transitions in early mammalian development


New York University
Sponsor: Da-Neng WangElectron tomography of hair cell stereocilia


University of California, San Francisco
Sponsor: Keith R. Yamamoto and Cynthis R. KenyonAnalyysis of regulation of steroid receptor activity


New York University
Sponsor: H.R. HoreckerCarbohydrate metaboism of bacteria


Harvard University Medical School
Sponsor: Norbert PerrimonCharacterization of the Drosophila unpaired receptor


University of California, San Francisco
Sponsor: Zachary KnightIdentification of homeostatic signals that regulate AgRP "hunger" neurons


Massachusetts General Hospital
Sponsor: Joshua M KaplanMolecular basis of synapse elmination in C elegans


University of California, Berkeley
Sponsor: Richard M. HarlandExpression cloning of murine inducing factors


MRC Center, University Medical School, England
Sponsor: Aaron KlugElectron Microscopy


University of California, Berkeley
Sponsor: David M. GreenbergIsotope tracer studies


Princeton University
Sponsor: Mala MurthyAuditory coding contributing to drosophila courtship behavior


Stanford University
Sponsor: Thomas RandoA comparative genomic analysis of lifespan evolution in vertebrates


University of Minnesota
Sponsor: Don WetlauferEnergetics of protein structue


Reed College
Sponsor: Laurens N RubenTumor viruses


Stanford University School of Medicine
Sponsor: I.R. LehmanE. coli DNA polymerase


Brigham and Women's Hospital
Sponsor: Stephen J ElledgedCas9-mediated assembly of protein microarrays for viral diagnosis


University of California, Berkeley


Massachusetts Institute of Technology
Sponsor: Alan GrossmanRegulated movement of a transcription factor


Yale University School of Medicine
Sponsor: Pietro De CamilliInvestigation of a protein complex implicated in P14P synthesis in the brain


Massachusetts Institute of Technology
Sponsor: H. Robert HorvitzSex myoblast migration in C elegans


Yale University
Sponsor: Thomas A SteitzYeast hexokinase


Yale University
Sponsor: Jennifer DoudnaStructural studies of the signal recognition particle


Yale University
Sponsor: Jessica CardinControl of cortical inhibition by Nrg1-ErbB4 signaling


University of Basel, Switzerland
Sponsor: Alex SchierNeural plasticity underlying social dominance behavior in cichlids


Yale University
Sponsor: Charles RaddingGenetic recombination


Yale University
Sponsor: Alen Garen / Fotis Kafatos

Albert Einstein College of Medicine
Sponsor: Jerard HurwitzMolecular basis of differentiation


Princeton University
Sponsor: James E. RothmanIs a multisubunit complex involved in membrane function?


University of California, Berkeley
Sponsor: Robert TjianIsolation of RNA polymerase I associated TAF's

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Sydney Brenner and Francois Jacob

Harvard University School of Public Health
Sponsor: Robert FareseMechanisms of lipid droplet formation


National Institutes of Health
Sponsor: Gary FelsenfeldNucleosome structure


National Cancer Institute
Sponsor: Walter C SchneiderBiosynthesis of desoxycytidine

California Institute of Technology
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California Institute of Technology
Sponsor: Dianne NewmanThe role of hopanoids in plant-microbe symbioses, with Dianne Newman


University of Washington
Sponsor: Julie TheriotFunctional genomics of directed 3D cell migration


Harvard University Medical School
Sponsor: Christopher T WalshMolecular investigations of microcin B-17


University of California, Berkeley
Sponsor: John E HearstSynthesis of analogs of psoralen


Whitehead Institute for Biomedical Research
Sponsor: Gerald R FinkTRPB gene regulation in Arabidopsis thaliana

Massachusetts Institute of Technology
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Massachusetts Institute of Technology
Sponsor: Tyler E JacksCells of origin and stem cells in lung adenocarcinoma


Stowers Institute for Medical Research
Sponsor: Alejandro Sanchez-AlvaradoCell fate and intercellular signaling in planarian regenerative organizers


Harvard University
Sponsor: Nancy KlecknerRole of host factors in Tn10 transposition


National Institutes of Health
Sponsor: Robert TyckoTransmembrane peptides studied by solid state NMR


Massachusetts Institute of Technology
Sponsor: Carl O PaboStructural studies of DNA replication initiation


Johns Hopkins University
Sponsor: Carl O PaboCrystallographic study of gene-regulatory


Hammersmith Hospital, England
Sponsor: William HayesRecombination in E coli


Harvard Medical School
Sponsor: Fred Winston and Dan GottschlingGenetics of transcription initiation in S. cerevisiae


University of Washington
Sponsor: Leland H HartwellDNA replication in Saccharomyces cerevisiae


University of California, San Diego
Sponsor: S. J. SingerMechanisms of biogenesis of membrane proteins


Whitehead Institute for Biomedical Research
Sponsor: Gerald R FinkIsolate and characterize genes that specify the spindle pole in body yeast


University of Colorado, Boulder
Sponsor: Thomas CechHolding on for dear life: primer binding and processivity in Tetrahymena thermophila telomerase


University of California, Berkeley
Sponsor: Eva NogalesStructure and dynamic of assembly of septin filaments


California Institute of Technology
Sponsor: David BaltimoreRegulation of mitochondrial fusion


University of Colorado, Boulder
Sponsor: Thomas R CechMolecular recognition of duplex RNA by a peptide


University of Virginia
Sponsor: Oscar L MillerImmunoelectron microscopy


Beth Israel Deaconess Medical Center
Sponsor: Pier Paolo PandolfiRole of circular RNAs in prostate cancer development and progression


University of California, San Francisco
Sponsor: William DeGradoDesign of peptides to target protein-protein interfaces of membrane fusogens

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Dabid BlowStructural aspects of membrane proteins


University of California, San Francisco
Sponsor: Andrew W MurrayCell cycle regulation of chromosome condensation


New York University
Sponsor: Severo Ochoa

California Institute of Technology
Sponsor: Michael ElowitzGene regulatory dynamics of cell differentiation


University of California, Irvine
Sponsor: Scott E FraserPatterning and segmentation in the nervous system

Whitehead Institute for Biomedical Research
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Whitehead Institute for Biomedical Research
Sponsor: David SabatiniDiet-dependent regulation of tumor growth through stroma metabolism


Massachusetts General Hospital
Sponsor: Jonathan WhetstineHistone lysine tri-demethylases regulate cell cycle progression


Universite de Geneve, Switzerland


Harvard University
Sponsor: Stuart L SchreiberExplore Fas signaling with a synthetic trimerizer


Stanford University
Sponsor: James A SpudichMeasurement of myosin movement along actin filaments


University of Colorado, Boulder
Sponsor: Larry SollCharacterization of E coli translational mutants


University of California, Santa Barbara
Sponsor: John CarbonProtein binding to yeast centromeric DNA

Imperial Cancer Research Fund Laboratories, England
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Imperial Cancer Research Fund Laboratories, England
Sponsor: G S MartinVirons of RNA tumor viruses


University of California, San Francisco
Sponsor: Dyche MullinsParM plays a central role in bacterial plasmid segregation

University of California, San Francisco
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University of California, San Francisco
Sponsor: Cynthia KenyonGermline rejuvenation in C. elegans


University of California, San Francisco
Sponsor: Jonathan WeissmanRegulation of gene expression by ribosomal proteins

University of California, Berkeley
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University of California, Berkeley
Sponsor: Nicole KingGenetic regulation of multicellularity in a close relative to metazoans


University of Washington, Seattle
Sponsor: Herschel L RomanMolecular analysis of yeast DNA


University of Wisconsin, Madison
Sponsor: Judith E KimbleCharacterization of signal transductions


Massachusetts Institute of Technology
Sponsor: Joe Sanbrook - David BaltimorekPost-transcriptional controls of animal viruses


Stanford University School of Medicine
Sponsor: Laura AttardiConsequences of P52 activation during development


Fred Hutchinson Cancer Center
Sponsor: James R PriessEarly determinants of neuronal fate in the nematode


University of Pennsylvania
Sponsor: Roberto BonasioMolecular regulation of behavioral and reproductive plasticity in ants


Australian National University, Australia


Rockefeller University
Sponsor: Gerald M EdelmanMolecular mechanisms of cel-cell interactions


Stanford University
Sponsor: Howard SchulmanCalmodulin binding and trapping by CaM kinase II


Massachusetts General Hospital
Sponsor: Randall PetersonDriving differentiation of retinal glia


Stanford University
Sponsor: James E RothmanATP-dependent clathrin disassembly


University of Colorado, Boulder
Sponsor: Ding XueRole of mitochondria during apoptosis in C elegans


Stanford University
Sponsor: Paul BergNucleic acid metabolism and protein synthesis


Stanford University
Sponsor: Karlene CimprichMechanisms of R-loop mediated innate immune response in non-dividing cells


Washington University in St. Louis
Sponsor: Stuart KornfeldMitogenic effects of certain lectins


University of Washington, Seattle
Sponsor: Charles LairdDosage compensation in Drosophila LSPI-alpha gnes


St. Jude Children's Hospital
Sponsor: Schulman, BrendaAnaphase-promoting complex ubiquitination mechanisms

Massachusetts Institute of Technology
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Massachusetts Institute of Technology
Sponsor: Tania BakerElucidating the role of the E. coli Lon protease N-domain in substrate recognition and discrimination


University of Oregon
Sponsor: George F. Sprague JrReceptor-mediated signal transduction in yeast


Brigham and Women's Hospital
Sponsor: Stephen J ElledgeThe role of ZNF292 in senescence and tumorigenesis


Harvard University
Sponsor: Tom Maniatisd. melanogaster tra-2 funtion in the male germ line


Yale University
Sponsor: Edward AdelbergQuantitation of chromosomal content in cell fusion hybrids


Cold Spring Harbor Laboratory
Sponsor: David ZipserTemperate phage Mu-1 in chromosome replication


Cold Spring Harbor Laboratory
Sponsor: David ZipserTemperate phage Mu-1 in chromosome of E. coli

University of California, Los Angeles
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University of California, Los Angeles
Sponsor: Leonid KruglyakA novel bulk segregant method to identify natural genetic variants underlying Caenorhabditis elegans resistance to chemotherapy drugs


Massachusetts Institute of Technology
Sponsor: Tyler JacksInvestigating mechanisms of immune evasion in autochthonous lung tumors


University of Washington, Seattle
Sponsor: Leland HartwellGenetic analysis of centromere replication


National Institutes of Health


University of Oxford, England
Sponsor: June LascellesTumor enzymology


Yale University
Sponsor: Mark SolomonCell cycle control by regulated protein degradation


University of California, Los Angeles
Sponsor: Julie Feigon, Juli FeigonNMR Studies of the hairpin ribozyme


Harvard University
Sponsor: Richard LosickBacterial biofilm regulation by D-amino acids


University of California, Berkeley
Sponsor: Wayne Hubbell - Harden M McConnellElectrical properties of niological membranes


University of Oregon, Eugene
Sponsor: Diana Libuda - Co-Sponsor Bruce BowermanDefining mechanisms of heat-sensitive synaptonemal complex in spermatocytes


University of California, San Francisco
Sponsor: Keith MostovActin cytoskeleton reorganization during tubulogenesis


Baylor College of Medicine
Sponsor: Allan BradleyGenome-wide monitoring of genetic changes in cancer development


Stanford University
Sponsor: George R StarkChromosomal organization

Chemisches Institut der Universitat, Switzerland
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Chemisches Institut der Universitat, Switzerland
Sponsor: Hans SchmidCarcinogenesis


University of Oregon
Sponsor: Bruce BowermanThe mechanism of cytokinesis


Rockefeller University
Sponsor: C. David AllisMetabolic connections to pluripotent chromatin


King's College, London
Sponsor: Geoffrey L BrownViral and bacterial DNA


Massachusetts Institute of Technology
Sponsor: David BotsteinRegulation of sucrose utilization in yeast

Swiss Institute of Experimental Cancer Research, Switzerland
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Swiss Institute of Experimental Cancer Research, Switzerland
Sponsor: Bernhard HirtAffinity chromatography


University of California, Berkeley
Sponsor: Jay D KeaslingControlling metabolic pathways with RNA aptamers


University of California, Santa Barbara
Sponsor: John A CarbonYeast centromere structure and function


Beatson Institute for Cancer Research, Scotland
Sponsor: John PaulDNA template activity


University of California, San Francisco
Sponsor: Ronald Vale

Harvard University Medical School
Sponsor: Michael GreenbergZinc finger TFs in activity-dependent human neuronal gene regulation


California Institute of Technology
Sponsor: Robert L SinsheimerChemical structure of RNA from tobacco mosaic virus


Harvard University Medical School
Sponsor: Tom A RapoportMolecular mechanisms to degrade abnoraml proteins


Stanford University School of Medicine
Sponsor: Patrick O. BrownInvestigation of asymmetric RNA localization


University of California, San Francisco
Sponsor: Frank McCormickNovel effectors of oncogenic KRAS that regulate cell signaling

Stanford University School of Medicine
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Stanford University School of Medicine
Sponsor: Tony Wyss-CorayEffects of irradiation injury on systemic-neurogenic communication as targets for limiting cognitive dysfunction


Yale University
Sponsor: George Palade - Wayne HubbellRelease of secretory proteins


University of California, Los Angeles
Sponsor: S Larry ZipurskyGenetic screen for regulators of neural connectivity


Harvard University
Sponsor: William McClure

Massachusetts Institute of Technology
Sponsor: Richard C MulliganDevelopmental neurobiology


Duke University
Sponsor: J E Boynton - N W GilhamChlamydomonas genes in chloroplast DNA repair


University of California, Berkeley
Sponsor: Joshua Kaplan

Harvard University
Sponsor: Richard M. LosickMulticellularity in Bacillus subtilis


Salk Institute for Biological Studies
Sponsor: Ronald M EvansIdentification of putative retinoic acid cistrans isomerase


Universite de Paris, France
Sponsor: Pierre SchafferRegulation of cellular differentiation in B. subtilis


Massachusetts Institute of Technology
Sponsor: H Robert Horvitz - Barbara J MeyerGenetic control of cell lineage in c. elegans


University of Washington, Seattle


Insitut for Biochemie, Max-Planck-Institut
Sponsor: F LynenSyntesis of steroids


Whitehead Institute for Biomedical Research
Sponsor: Peter S KimStructural basis of membrane fusion in HIV infection


Massachusetts Institute of Technology
Sponsor: Stephen J LippardFluorescent probes for the roles of NO in cancer


University of California, Berkeley
Sponsor: Jay D KeaslingEngineering E coli for production of anticancer drug


Yale University
Sponsor: Ruslan MedzhitovSensing gut microbiota through G-protein coupled receptors


Harvard University Medical School
Sponsor: Stephen HarrisonSingle particle flavivirus membrane fusion


Harvard University
Sponsor: Jonathan G SeidmanStructure and biology of genes in the murin S region

Carnegie Institute for Science
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Carnegie Institute for Science
Sponsor: Steven L McKnightMechanisms of transcriptional activation by C/EPB

Whitehead Institute for Biomedical Research
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Whitehead Institute for Biomedical Research
Sponsor: Harvey F LodishAnalysis of the adipocyte glucose transporter

Centre Nationale de la Recherche Scientifique, France
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Centre Nationale de la Recherche Scientifique, France
Sponsor: J SxulmajsterBiosynthetic pathway of DPA in B. subtilis

University of California, San Diego
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University of California, San Diego
Sponsor: Arshad DesaiDissecting kinetohore function in C Elegans


Michigan State University
Sponsor: Joseph E VarnerAction of gibbrelin on germination enzymes


Harvard University Medical School
Sponsor: Galit LahavMolecular dynamics of oncogene-induced senescence


Dana-Farber Cancer Institute
Sponsor: Bruce SpiegelmanThe role of Kcnk3 and membrane potential in adipose tissue thermogenesis


University of California, San Francisco
Sponsor: Holger WillenbringUnderstanding liver bile duct formation to grow biliary tubes in vitro


Stanford University
Sponsor: Judith FrydmanDissecting the protein folding mechanism by the TRiC chaperonin


University of California, San Francisco
Sponsor: Jonathan WeissmanSystemic analysis of the relationship between incRNAs and translation


Stanford University
Sponsor: Anne BrunetDissecting the mechanisms of vertebrate reproductive aging in killfish


Rockefeller University
Sponsor: Hidesaburo HanafusaViral carcinogenesis


Scripps Research Institute
Sponsor: Richard A LernerCatalytic antibodies


Harvard University
Sponsor: Doug Melton

Stanford University
Sponsor: Mark A. KrasnowMechanism of airway tube size control during lung development


Harvard University Medical School
Sponsor: Peng YinRNA circuits for cancer theranostics


Rockefeller University
Sponsor: James E Darnell JrTurnover mRNA


University of Cambridge, England
Sponsor: Michael Ashburner and Carroll M. WilliamsEcdysone action in Drosophila


University of California, San Francisco
Sponsor: Yuh Nung Jan

Massachusetts Institute of Technology
Sponsor: Tania BakerConservation of AAA:+ protease substrates


University of Kansas
Sponsor: Robert E StowellTransplantation of mouse tumors


Stanford University
Sponsor: Lucy ShapiroExploring the role of kinase subcellular localization in bacterial cell cycle regulation


Stanford University
Sponsor: Laurence Kedes

Harvard University Medical School
Sponsor: Johannes WalterProbing the dynamics of the eukaryotic replicative helicase


Stanford University
Sponsor: Mark A KrasnowIndentification of an inducer of tracheal branching

Oregon Health and Science University, Portland
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Oregon Health and Science University, Portland
Sponsor: Eric GoauxStructure of the NR1-NR2 subtype of the NMDA receptor in the open state


University of California, Berkeley

Whitehead Institute for Biomedical Research
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Whitehead Institute for Biomedical Research
Sponsor: Gerry Fink

Stanford University
Sponsor: Paul BErgCan yeast genes rescue Xeroderma


Boston Children's Hospital
Sponsor: Frederick W AltMechanism and machinery of class switch recombination


University of Utah School of Medicine
Sponsor: Cedric Feschotte & Nels EldeCo-option of endogenous retroviruses for host immune responses


University of Wisconsin, Madison
Sponsor: Marvin Wickens

University of California, Los Angeles
Sponsor: S Lawrence ZipurskyAnalysis of connectivity in the Drosophila eye


Stanford University
Sponsor: Thomas ClandininVisual feedback modulation in behaving Drosophila


University of California, Berkeley
Sponsor: David BilderThe polycomb family of epigenetic transcriptional repressors and their role in Drosphila growth control


Stanford University
Sponsor: Jeffrey L SklarDiagnosis of lymphoma based on lg gene rearrangements


University of California, San Francisco
Sponsor: Louis F ReichardtNeuronal development


University of Switzerland, Zurich
Sponsor: Charles WeissmannRNA tumor-virus infection


Washington University in St. Louis
Sponsor: Rob MitraProtein sequencing through single molecule detection


University of California, San Francisco
Sponsor: Marc Tessier-LavigneAnalysis of semaphoring in C. elegans and vertebrates


University of California, San Francisco
Sponsor: Stanley B. PrusinerStructural basis of synthetic prion infectivity


Fred Hutchinson Cancer Center
Sponsor: James M RobertsCell cycle with the use of transcriptional arrays


University of Massachusetts Medical School
Sponsor: Lynne ReganRabGDI displacement factors: mechanism and function in membrane traffic


Harvard University


University of California, San Diego
Sponsor: Donal HelinskiBaterial episomal DNA


University of California, Berkeley
Sponsor: Jennifer DoudnaDeveloping new CRISPR-Cas system for eukaryotic RNA knockdown and detection


Pennsylvania State University
Sponsor: Joseph J VillafrancaInactivation of dopamine - beta hydroxylase


Massachusetts Institute of Technology
Sponsor: Rudolph JaenischOncogenes


Massachusetts Institute of Technology
Sponsor: H. Robert Horvitz

Whitehead Institute for Biomedical Research
Sponsor: Peter ReddienThe origin and evolution of cell types


University of Wisconsin, Madison
Sponsor: Howard TeminRNA tumor virus DNA


Whitehead Institute for Biomedical Research
Sponsor: Harvey LodishIdentification and characterization of receoptors in the endoplasmic reticulum


University of Washington
Sponsor: Evan EichlerStratifying genomic variation to increase power in genetic association studies of common human diseases


Stanford University
Sponsor: Tim StearnsAnalysis of centrosome duplication in human cells


University of Washington
Sponsor: David BakerComputational design of eukaryotic signal transduction


Baylor College of Medicine
Sponsor: Stephen J. ElledgeIdentification and analysis of APC substrates


Cornell University
Sponsor: Thomas D FoxGene expression


Sidney Farber Cancer Institute
Sponsor: J.L. StromingerStructure of human thymus-leukemia-like antigens


University of California, Berkeley
Sponsor: Christopher ChangIntersection of nitric oxide and copper-mediated signaling pathways in mammalian cells


Stanford University
Sponsor: Sharon Long

Albert Einstein College of Medicine
Sponsor: William R Jacobs, JrIdentification of genes involved in mycobacterial virulence


University of California, San Francisco
Sponsor: Yuh Nung JanMolecular mechanisms of dendritic morphogenesis


University of Colorado, Boulder
Sponsor: David Hirsh

Peter Bent Brigham Hospital
Sponsor: G W ThornPathophysiological significance of aldosterone in man


Johns Hopkins University


Boston Children's Hospital
Sponsor: Stuart H. Orkin, Stuart H OrkinThe role of GATA-1 in hematopoiesis


University of California, Los Angeles


Cornell University
Sponsor: Gerry Fink

University of North Carolina, Chapel Hill
Sponsor: R.V. WofendenSynthesis of potent enzyme inhibitors


Stanford University


University of California, Los Angeles
Sponsor: Ren Sun & James Lloyd-SmithForecasting evolution of drug resistance in hepatitis C virus


University of California, San Francisco
Sponsor: Hiten MadhaniUncovering the molecular drivers of lethal invasive fungal infection


Princeton University
Sponsor: Tom MuirDefining the interactome of the acidic patch with chromatin effectors


Massachusetts Institute of Technology
Sponsor: Matthew Vander HeidenUnderstanding cellular and organismal amino acid homeostasis

National Institute for Medical Research, England
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National Institute for Medical Research, England
Sponsor: M R PollckIsolation of variant B. subilis


University of Washington
Sponsor: David BakerPrediction of novel protein folds at high resolution


Massachusetts Institute of Technology

Harvard University Medical School
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Harvard University Medical School
Sponsor: Jon ClardyMolecular messages in algal-bacterial symbiosis

King's College, University of London, England
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King's College, University of London, England
Sponsor: H HarrisEucaryotic transcription factors


Harvard University Medical School
Sponsor: John J. MekalanosMapping virulence regulatory and signaling networks in vibrio cholera


Scripps Research Institute
Sponsor: James WilliamsonEvolutionary profile of ribosome biogenesis

Centre Nationale de la Recherche Scientifique, France
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Centre Nationale de la Recherche Scientifique, France
Sponsor: Pietter ChambonGene Expression


Massachusetts Institute of Technology
Sponsor: James R WilliamsonStructure and dynamics of an rRna-protein complex by NMR


University of California, San Francisco
Sponsor: Christine GuthrieGenetic analysis of messenger RNA transport


Yale University
Sponsor: Bernard G ForgetMolecular genetics of human hemoglobin synthesis

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: J B GurdonRegulation of gene expression

University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center
Sponsor: Michael S Brown & Joseph GoldsteinSite-2 protease for SREBPs: biochemical characterization


Harvard University Medical School
Sponsor: Marc W. KirschnerA systems biology analysis of the DNA damage response


Harvard University
Sponsor: Xiaowei ZhuangMechanistic studies of ATP-dependent chromatin remodeling enzymes


University of California, Berkeley
Sponsor: John W GofmanHuman serum lipoproteins

La Jolla Institute for Allergy and Immunology
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La Jolla Institute for Allergy and Immunology
Sponsor: Anjana RaoTET loss-of-function and R-loops-mediated genomic instability in cancer


Scripps Research Institute
Sponsor: Benjamin CravattChemoproteomic discovery of small-molecule probes for autophagy proteins


Salk Institute for Biological Studies
Sponsor: Edwin LennoxCell-cell interaction


Harvard University Medical School
Sponsor: Samara Reck-PetersonInvestigating dynein-mediated viral transport


Massachusetts Institute of Technology
Sponsor: David BaltimoreImmunoglobulin heavy chain gene rearrangement


University of Vermont
Sponsor: Janet Kurjan

University of California, Berkeley
Sponsor: Tracy HandelRedesigning the hydrophobic cores of proteins


Institut Pasteur, France
Sponsor: Francois Jacob

Harvard University
Sponsor: David LiuContinuous directed evolution of proteases for cancer therapy


University of California, San Francisco
Sponsor: Graeme DavisGenetic dissection of synaptic homeostasis


Harvard University
Sponsor: Tom ManiatisIn viro mutagenesis of cloned globin genes


Massachusetts Institute of Technology
Sponsor: Harvey F LodishGene Expression


Massachusetts Institute of Technology
Sponsor: Graham C WalkerDNA damage into mutations


Harvard University Medical School
Sponsor: Ed HarlowSynthetic lethal interactions in cancer


University of California, Berkeley


Cornell University
Sponsor: Gerry Fink

University of California, San Francisco
Sponsor: Ronald ValeProbe the interplay between actin cytoskeleton and immunoreceptor signaling


University of California, Berkeley
Sponsor: John H. Gerhart

University of Chicago
Sponsor: Ed Munro and Sally Horne-BadovinacDissecting mechanical feedback in the Drosophila egg chamber


Whitehead Institute for Biomedical Research
Sponsor: Robert A WeinbergIntiation-promotion in carcinogenesis


University of California, Berkeley
Sponsor: David DrubinInvestigation of dynamin's role in the temporal regulation of actin remodeling during endocytic vesicle formation


Stanford University
Sponsor: Charles YanofskyProtein structure and function


Fred Hutchinson Cancer Center
Sponsor: Harmit MalikCauses and consequences of a non-canonical H2A variant in flies


Stanford University
Sponsor: Karlene CimprichMolecular dissection of the replication checkpoint


Fred Hutchinson Cancer Center
Sponsor: Daniel E GottschlingIn vivo analysis of silent chromatin domains


National Institutes of Health
Sponsor: Michael LenardoTrancscriptional control of helper T-cell development


University of Pennsylvania


Johns Hopkins University
Sponsor: John J Cebra and John NiederhuberHapten specific tolerance


Washington University in St. Louis
Sponsor: David KirkControl of reproductive cell fate in Volvox carteri


Massachusetts General Hospital
Sponsor: Robert A KingstonFunction of histone ubiquitination in chromatin regulation


Stanford University School of Medicine
Sponsor: James Spudich
MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Cesar MilsteinImmunoglobulin mRNA


Washington University in St. Louis
Sponsor: Stuart Kornfeld

Harvard University Medical School
Sponsor: Wade Harper Co-Sponsor Joseph ManciasSystemic analysis of the mammalian selective autophagy cargo network


University of California, San Francisco
Sponsor: Thomas Komberg

Rockefeller University
Sponsor: Zanvil Cohn

University of Wisconsin, Madison
Sponsor: Antony O W StrettonNMR studies of the neurobiology of Ascaris suum


Stanford University
Sponsor: David S. Hogness

Massachusetts Institute of Technology
Sponsor: David Botstein
MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Richard Henderson
International Laboratory of Genetics and Biophysics, Italy
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International Laboratory of Genetics and Biophysics, Italy
Sponsor: P. Amati

Albert Einstein College of Medicine
Sponsor: Julius Marmur

Stanford University
Sponsor: I.R. LehmanE coli restriction enzyme


Massachusetts Institute of Technology
Sponsor: Leonard Guarente

Stanford University
Sponsor: Ronald W DavisStructure of Tyl RNA


California Institute of Technology
Sponsor: Leroy Hood

Brigham and Women's Hospital
Sponsor: Stephen J. ElledgeHarnessing lysine acetylation and methylation in the DNA damage response


Stanford University
Sponsor: Gerald R. CrabtreeATP-dependent chromatin remodeling in dendritic morphogenesis and targeting


University of Wisconsin, Madison
Sponsor: Judith Kimble

Yale University
Sponsor: G. Shirleen Roeder

National Cancer Institute
Sponsor: David H SachsCharacterization of Ia antigens


University of Virginia
Sponsor: Alan O. BerglandGenetics and evolution of photoperiodism in Drosophila melanogaster


Harvard University Medical School
Sponsor: Roy KishonyProbing complex microbial communities: structure and response to perturbations with antibiotics


Rockefeller University
Sponsor: Elaine FuchsStem Cell migration during wound-induced reepithelialization


Salk Institute for Biological Studies
Sponsor: Fred GageInflammation and Parkinsons disease


Harvard University Medical School
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Whitehead Institute for Biomedical Research
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Whitehead Institute for Biomedical Research
Sponsor: Eric S LanderParallel analysis of gene expression


Columbia University
Sponsor: Wayne A HendricksonStructure of follicle stimulating hormone receptor

National Institute for Medical Research, England
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National Institute for Medical Research, England
Sponsor: Robin Holliday

Harvard University
Sponsor: Alexander SchierNovel signaling peptides in zebrafish development


University of California, San Francisco
Sponsor: Barbara Panning/ Michael BishopLodestar: a metazoan-specific chromatin remodeler

University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center
Sponsor: Errol C FriedbergRole of CSA and CSB in transcription/repair coupling


Karolinska Institutet, Sweden
Sponsor: Klein, GeorgeInvestigations concerning cell growth, survival and destruction in a transplantation situation


University of California, San Francisco
Sponsor: Patrick H O'FarrellNitric oxide signaling in the hypoxic response


Washington University School of Medicine
Sponsor: Joshua R SanesRetinotectal synapse formation in transgenic mice


Massachusetts Institute of Technology
Sponsor: Chris BurgeImpacts of splicing perturbations on transcriptional programs in cancer


Yale University
Sponsor: Jennifer A DoudnaAtomic structure of group II self-splicing introns


University of California, San Diego
Sponsor: Peter WolynesCoupled folding and binding of IkB-alfa


Stanford University
Sponsor: Irving L WeissmanT cell differentiation


Stanford University
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University of Colorado, Boulder
Sponsor: Mark WineyCharacterization of the mouse Mps 1p-like Esk kinase


Whitehead Institute for Biomedical Research
Sponsor: Rudolf JaenischFormation of phase separated condensates in fragile X-Linked syndromes


Stanford University
Sponsor: D O WoodwardMitochrindiral biogenesis in Neuospora crassa


Dana-Farber Cancer Institute
Sponsor: Richard D KolodnerCharacterization of a eukaryotic mismatch repair pathway


Cornell University
Sponsor: Thomas Fox

MRC Center, University Medical School, England
Sponsor: Greg Winter

Salk Institute for Biological Studies
Sponsor: Ronald M. Evans

Yale University
Sponsor: Sidney Altman

National Institutes of Health
Sponsor: Harvey B Pollard, NIH and Vann Bennett The Johns Hopkins UniversityMechanisms of membrane fusion


Oxford University, England
Sponsor: Nigel Grindley, Oxford University England and Chris Dobson, Yale UniversityNMR analysis of alamethicin conformation in micelles


Carnegie Institute for Science
Sponsor: Allan SpradlingDrosophila hindgut stem cells: uncovering their roles in tissue formation as well as tissue maintenance


National Institutes of Health
Sponsor: Ronald H SchwartzT Cell activation


University of California, San Francisco
Sponsor: Demetrios PapahadjopoulosLiposome-mediated insertion of nucleic acids into cells


Massachusetts General Hospital
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Case Western Reserve University
Sponsor: John SpizienNucleic acids of microorganisms


University of Michigan
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Stanford University
Sponsor: C. Garrison FathmanIsolation and characterization of T cell receptors


Weizmann Institute of Science, Israel
Sponsor: Ernest WinocourCarcinogenesis


Stanford University School of Medicine
Sponsor: Steven ArtandiTelomerase trafficking as anti-cancer target


Cambridge University, England
Sponsor: Alexander ToddElucidation of mechanisms of enzyme action


Yale University


Yale University


University of California, Davis
Sponsor: Jodi NunnariLateral organization of mitochondrial membranes


University of California, San Francisco
Sponsor: Christoph SchreinerDisruption of neural circuits by environmental toxins


Yale University School of Medicine


Indiana University


Stanford University


Columbia University


MRC Center, University Medical School, England
Sponsor: Sydney BrennerDifferentiation of hemopoietic cells

University of Southern California, Los Angeles
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University of Southern California, Los Angeles
Sponsor: Myron F GoodmanThe biochemical basis of DNA synthesis fidelity


Lawrence Berkeley National Laboratory
Sponsor: Eva Nogales & Carlos BustamanteMechaochemistry of transcription-couple DNA repair


University of California, San Francisco
Sponsor: Cornelia BargmannActivity-dependent axon outgrowth: a genetic approach


Princeton University
Sponsor: Mark D RoseDNM1, a dynamin-related gene, participates in endosomal trafficking in yeast


University of Cambridge, England
Sponsor: Alfonzo M AriasComparative studies of developmental mechanisms

University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center
Sponsor: Youxing JiangRole of two pore channels in NAADP-induced Ca2+ signaling


California Institute of Technology
Sponsor: Seymour BenzerGenetic studies of behavior in Drosophila


Scripps Research Institute
Sponsor: Clare Waterman-StorerMechanical feedback in cell motility


University of California, Berkeley
Sponsor: Carolyn BertozziThe role of tuberculosis sulfatases in virulence

Public Health Research Institute of the City of New York
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Public Health Research Institute of the City of New York
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Whitehead Institute for Biomedical Research
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Fred Hutchinson Cancer Center
Sponsor: David M. HockenberyThe role of fructose in breast cancer growth by investigation of transcriptional regulation


Rockefeller University
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University of California, Berkeley
Sponsor: Randy SchekmanThe origin of the autophagosomal membrane

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Sydney Brenner

Yale University
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Yale University
Sponsor: Frederic M RichardsTransient vs stable membrane protein complexes


University of California, San Francisco
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Stanford University
Sponsor: Paul BergAmino acid activating enzyme - tRNA recognition


University of British Columbia, Vancouver
Sponsor: Lawrence B Mcintosh, Lawrence B McIntoshIntramolecular inhibition of DNA binding of ethe Ets-1 ETS domain


Stanford University
Sponsor: Paul BergtRNA recognition


Max-Planck Institute
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Princeton University
Sponsor: Eric WeischausMarking genetic mosaics directly in late embryos


National Institutes of Health
Sponsor: C B AnfinsenKinetic study of staphylococcal nuclease fragments


Stanford University
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Carnegie Institute for Science
Sponsor: Allan SpradlingRepair and regeneration of Drosophila musculature: a potential role for muscle stem cells


Salk Institute for Biological Studies
Sponsor: Tony HunterRole of aPKC in cell migration during neurulation


Harvard University Medical School
Sponsor: Norbert PerrimonMolecular-genetic analysis of squamous epithileal morphogenesis


California Institute of Technology
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University of California, Berkeley


Cold Spring Harbor Laboratory
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University of Wisconsin, Madison
Sponsor: Howard M TeminTransformation by Rev-T

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University of California, San Francisco
Sponsor: Ronald D. ValeUnderstanding mitochondrial trafficking: linking mitochondria to motors


University of Washington, Seattle
Sponsor: R D PalmiterRegulation of expression of ovalbumin gene


Weizmann Institute of Science, Israel
Sponsor: E. Katalski and F. SangerCorrelation of nucleic acid to protein structure


Stanford University
Sponsor: Daniel HerschlagComparative approach to uncover mechanisms of RNA molecular recognition


Johns Hopkins University
Sponsor: Edward C HeathBiosynthesis of the lipid portion of the cell wall lipopolysaccharide of E. Coli


University of California, Berkeley
Sponsor: Robert TjianHuman TAFII250 bromodomain function in transcription


Cold Spring Harbor Laboratory
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Massachusetts Institute of Technology
Sponsor: Tyler JacksDissecting tumor-stroma interactions in lung cancer


Yale University
Sponsor: Clyde DemingAtypical growth research unit tumors of the genito-urinary system


Massachusetts Institute of Technology
Sponsor: David BaltimoreIsolation and characterization of MuLV mutants


Stanford University
Sponsor: Nigel T UnwinElectron microscopy of gap junctions


New York University
Sponsor: Jerard HurwitzNucleic acid synthesis

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Peter A LawrenceGenetic analysis of Drosophila eye development


Harvard University Medical School


Stanford University
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University of Chicago
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Stanford University School of Medicine
Sponsor: Gerald CrabtreeCharacterization of a novel 4 Mda oncogenic complex


Massachusetts Institute of Technology
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California Institute of Technology
Sponsor: Elliot MeyerowitzCell-cell interactions and regulation of cell division in floral meristems of A thaliana


Massachusetts Institute of Technology
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Stanford University
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University of California, San Francisco
Sponsor: Jeffrey BluestoneMapping and manipulating T-cell plasticity via synthetic receptor libraries


Yale University
Sponsor: Harry S.N. GreeneMetabolism of radioactive iodine in lower chordates and the problem of homology of the thyroid gland


Chester Beatty Research Institute, England
Sponsor: A. Haddow

University of Glasgow, Scotland
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Rockefeller University
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National Cancer Institute
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University College, England
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University of Oxford, England
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Brown University
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University of Pennsylvania
Sponsor: Arjun RajCellular states guiding plasticity and reprogramming paradigms in cancer


Massachusetts Institute of Technology
Sponsor: Hermann StellerFunctional and mutational analysis of Drosophila IAP's


Duke University
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University of California, Berkeley
Sponsor: Xavier Darzacq and Robert TjianIn-Vivo single-molecule imaging of enhancer-promoter communication


Yale University
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Harvard University
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Harvard University Medical School
Sponsor: Bernardo SabatiniMultilingual neurons: GABA corelease from cholinergic basal forebrain neurons


Harvard University
Sponsor: Tom ManiatisThe role of SR proteins in splicing enhancer function


Yale University


Carnegie Institute for Science
Sponsor: Allan SpradlingUnderstanding nuclear aging in the Drosophila follicle stem lineage


University of Heidelberg, Germany
Sponsor: Ekkehard K. Bautz4Eukaryotic transcription using antibodies prepared against eukaryotic RNA polymerases


MRC Center, University Medical School, England


Cornell University


Rockefeller University


New York University


Massachusetts Institute of Technology


Fox Chase Cancer Center
Sponsor: Ken ZaretHeterochromatin remodeling by ISNI-containing complexes


Massachusetts Institute of Technology


Whitehead Institute for Biomedical Research
Sponsor: David C. PageSexually dimorphic gene expression in human preimplantation development


Research Institute of Scripps Clinic


Albert Einstein College of Medicine
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California Institute of Technology
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Broad Institute
Sponsor: Ashlee EarlPioneering comparative regulomics to probe mechanisms of chronic salmonella


Stanford University
Sponsor: Michael SnyderIntegrated omics of malignant transformation by breast cancer genes, with Michael Snyder


Harvard University Medical School
Sponsor: George ChurchDeveloping cell-free platform for biosynthesis and metabolic engineering of cancer therapeutics


Harvard University


Stanford University


Brigham and Women's Hospital
Sponsor: Stephen ElledgeThe role of SASP regulator GATA4 in senescence and cancer


Massachusetts Institute of Technology
Sponsor: Michael LaubQuantitative dissection of how genome organization impacts gene expression


Massachusetts Institute of Technology
Sponsor: Frank B. GertlerAdhesion and cytoskeletal dynamics in neuron guidance


University of California, Berkeley


Stanford University
Sponsor: Peter SarnowNucleolin: RNA interaction during poliovirus infection


University of California, Berkeley


California Institute of Technology
Sponsor: Norman Davidson

Rockefeller University
Sponsor: Elaine FuchsMapping the translational landscape of tumor progression and immune evasion


Harvard University
Sponsor: Don C WileyMechanisms of mating system evolution in nematodes


University of Wisconsin, Madison
Sponsor: Judith KimbleMechanisms of mating system evolution in nematodes


Harvard University
Sponsor: Florian EngertCircuits mediating learning and sensory processing in the context of memory in zebrafish


Harvard University Medical School
Sponsor: Marc KirschnerBiochemical studies of the membrane-associated steps in the Wnt signaling pathway


Harvard University


Yale University


Yale University
Sponsor: Karin ReinischStructural and functional studies of RNA quality control TRAMP4 complex


University of California, Berkeley
Sponsor: Jennifer DoudnaRedesigning lentiviruses to achieve CRISPR-Cas9 genome engineering in vivo


Princeton University


University of California, San Francisco
Sponsor: Yuh Nung JanIdentification of the repulsive signals mediating dendritic tiling of class IV Drosophila

University of California, San Francisco
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University of California, San Francisco
Sponsor: Lily JanDynamics of RNA granule assembly in temperature synchronization of clock rhythms


Harvard University Medical School


Harvard University Medical School
Sponsor: David GintyThe physical and molecular determinants of touch


National Institutes of Health


Massachusetts Institute of Technology
Sponsor: Phillip Sharp

New York University


Boston Children's Hospital
Sponsor: Thomas SchwarzMechanism for activating the clearance of damaged axonal mitochondria


Harvard University
Sponsor: Bence OlveczkyInvestigating how striatum selects and modifies actions across contexts


California Institute of Technology
Sponsor: Tom Maniatis

Carnegie Institute for Science


Stanford University
Sponsor: W. James NelsonRole of APC multi-protein complex in regulating microtubule function at the membrane


Harvard University Medical School
Sponsor: Bert Vallee

Johns Hopkins University
Sponsor: William Lennarz

Stanford University
Sponsor: David Hogness

Columbia University
Sponsor: Richard AxelThe architecture and function of a neural circuit governing behavioral plasticity


University of Colorado, Boulder
Sponsor: David Prescott

University of California, Berkeley
Sponsor: Robert TjianIsolation and characterization of homeo box-containing genes


University of Washington School of Medicine
Sponsor: David BakerProbing the structural role of buried polar residues


National Institute for Medical Research, England
Sponsor: Vassillis PachnisGDNF/RET signaling roles in mammalian ENF development


State University of New York, Stony Brook
Sponsor: Thomas ShenkIsolation of Ad2 mutants


State University, Gent, Belgium
Sponsor: J. De LeyNucleic acid


University of California, Berkeley
Sponsor: Gerald M RubinMissexpression of the Drosophila rough gene interferes with normal eye develoment


Carnegie Institute for Science
Sponsor: Allan C SpradlingMultiple replication origins are used during Drosophila chorion gene amplification


University of California, Berkeley
Sponsor: Gerald M RubinMolecular and genetic analysis of the disconnected locus


Rockefeller University
Sponsor: Shai ShahamForm and function of glia-neuron interactions


University of California, San Diego
Sponsor: Juan YguerabideFluorescence mapping of chromosomal genes


Johns Hopkins University
Sponsor: Saul RosemanGlycolipids and glycoproteins of normal and transformed mammalian cells


Harvard University Medical School
Sponsor: Christopher T WalshRegulation of transcription by mercuric ion in a marine Bacillius


University of Edinburgh, Scotland
Sponsor: Julian GrossDNA polymerase and invitro DNA


State University of New York, Stony Brook
Sponsor: Gerald H ThomsenRegulation of Smad signaling of the TGF-beta signal transduction pathway by novel Smurf ubiquitin ligases


Harvard University
Sponsor: Frank WestheimerPhotoreactive diazo analogs of coenzymes


Whitehead Institute for Biomedical Research
Sponsor: Robert WeinbergTargeting the EMT program in high grade serous ovarian cancer


University of Colorado, Boulder
Sponsor: David PrescottDNA related proteins in the development of the macronucleus


Harvard University Medical School
Sponsor: Richard SidmanBasic mechanisms in the development of the mammalian central nervous system


Cambridge University, England
Sponsor: Alexander ToddOrganic phosphates


Harvard University
Sponsor: Tom ManiatisSplice site selection in alternative splicing


Stowers Institute for Medical Research
Sponsor: Ali ShilatifardHistone H3K79 methylation in development and cancer pathogenesis


Center for Blood Research, Boston
Sponsor: Timothy A SpringerCharacterization of the MAC-1 ligand on neutrophils


Fred Hutchinson Cancer Center
Sponsor: James R PriessGenetics of C. elegans pharyngeal development


University of California, Berkeley
Sponsor: Matthew WelchIlluminating novel actin cytoskeletal dynamics through a bacterial pathogen


University of California, San Francisco
Sponsor: Marc Tessier-LavigneIdentification of axonial chemotropic receptors


University of Basel, Switzerland
Sponsor: Gottfried SchatzFunction and biogenesis of peroxisome membrane


Harvard University Medical School
Sponsor: Charles RichardsonDNA replication in E. coli


Cornell University
Sponsor: Gerald R FinkCloning and sequencing of the HIS 1 locus in yeast


Harvard University Medical School
Sponsor: Eugene KennedyMetabolism and function of cardiolipin


Portsmouth Polytechnic, England
Sponsor: E M BradburyHistone I-DNA and histone IV-DN complexes


Massachusetts Institute of Technology
Sponsor: Harvey LodishDevelopment of D. discoideum


Harvard University Medical School
Sponsor: John F EndersMammalian viruses of normal and malignant cells


Stanford University
Sponsor: Karl DeisserothThe role of altered neural activity in brain aging and cognitive decline


Massachusetts General Hospital
Sponsor: F LipmannInterrelationships between metals and enzymes


Massachusetts Institute of Technology


Yale University
Sponsor: Seymour BenzerLambda prophage


Harvard University Medical School
Sponsor: Roberto KolterInteractions with dual species biofilms


King's College, London
Sponsor: Dennis BrayA novel microtubule-associated protein causes TP-sensitive aggregation of microtubules


University of Utah
Sponsor: Erik JorgensenIs PIP2 required for synaptic vesicle exocytosis or endocytosis?


Stanford University
Sponsor: Gerald R CrabtreeDissecting converging signalling pathways in T cell activation


Harvard University
Sponsor: Markus MeisterNeural mechanisms of mammalian pheromone recognition


Harvard University
Sponsor: Andrew W. MurrayExperimental evolution of symbiosis


University of Chicago
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Harvard University and Cold Spring Harbor Laboratory
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Harvard University and Cold Spring Harbor Laboratory
Sponsor: James D WatsonLife cycle of tumor virus SV40


University of California, Berkeley
Sponsor: David BilderEpithelial migration in the drosophila egg chamber


University of California, San Francisco
Sponsor: Wendell LimSynthetic chromatin: exploring the design principles


Harvard University School of Public Health
Sponsor: Brendan ManningRole of the P13K-mTOR signaling network in reprogramming lipid metabolism


Massachusetts Institute of Technology
Sponsor: Phillip A SharpBiochemical studies of Xist-mediated gene silencing


Harvard University
Sponsor: Connie HolmRole of CDC14 and a related check point in mitosis


Massachusetts Institute of Technology
Sponsor: Joel HubermanDNA synthesis in HeLa cells


Johns Hopkins University
Sponsor: William J. LennarzControl of ASN-linked oligosaccharide processing


Harvard University Medical School
Sponsor: Wade HarperSpatial and temporal organelle quality control during changes in cell state


National Cancer Institute
Sponsor: Michael M GottesmanFunctional expression and mutational analysis of human P-glycoprotein


Whitehead Institute for Biomedical Research
Sponsor: Gerald R FinkAnalysis of cell expansion regulation in Arabidopsis


Yale University School of Medicine
Sponsor: Ira MellmanMechanism of cell polarity in the sorting pathway


Washington University in St. Louis
Sponsor: Jay W PonderClosing the gap: Near-native folds to all-atom models


Stanford University
Sponsor: Liqun LuoSpatiotemporal dissection of BDNF-TrkB in circuit assembly


Rockefeller University
Sponsor: David LuckIsolation and characterization of conditions mutations affecting cellular neurotubules


University of California, San Francisco
Sponsor: Zev GartnerWithin and between-cell effects of driver mutations on breast tumor fitness


New York University
Sponsor: Dan R. LittmanStudying the epigenetic nature of CD4 silencing in fully committed cytotoxic T cells


Purdue University
Sponsor: S ArnottStructures and interactions of intercellular polysaccharides

Imperial Cancer Research Fund Laboratories, England
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Imperial Cancer Research Fund Laboratories, England
Sponsor: Robin A WeissGenetic structure of RNA tumor viruses


Harvard University Medical School
Sponsor: Norbert PerrimonThe role of organ communications in stem cell aging


Harvard University
Sponsor: Fotis KafatosTranslational control of cocoonase biosynthesis


University of Texas Southwestern Medical Center
Sponsor: Johann DeisenhoferNovel membrane protein crystallization reagents


Massachusetts Institute of Technology
Sponsor: H Robert HorvitzGenetic analysis of neuromodulators in nematode


Salk Institute for Biological Studies
Sponsor: Melvin CohnTumor antigens in murine myeloma cells


Stanford University
Sponsor: Paul BergEnzymology of nucleic acid metabolism


Harvard University
Sponsor: Fotis C KafatosChorion gene organization and expression in the Silkmoth Bombyx mari


Duke University
Sponsor: Irwin FridovichSuproxide production by respiring membranes of E. coli


University of California, San Francisco
Sponsor: Keith A Yamamoto, Keith R YamamotoFunctional analysis of oncogene/steroid receptor


University of California, Berkeley
Cofactor invocled in glutamate fermentation by Clostridium tetanomorphum as a Viatamin B12 derivative


Harvard University Medical School
Sponsor: Frederick M AusubelDissection of innate immunity in C elegans


Institut Pasteur, France
Sponsor: Pascale Cossart, Pascal CossartRole for phosphoinositide 3-kinase in bacterial invasion


University of Cambridge, England
Sponsor: Michael Akam and Ian SussexGenetic and molecular basis of positional specification


Stanford University
Sponsor: Stanley FalkowDNA sequencing


Harvard University Medical School
Sponsor: Yang ShiRoles of a histone demethylase SMCX in neuronal function


Harvard University
Sponsor: Matthew MeselsonMolecular basis of transvection in Drosophila


Harvard University
Sponsor: Stephen HarrisonStructure of spherical viruses


University of Massachusetts Medical School
Regulation of slime mold mRNA synthesis


Boston Children's Hospital
Sponsor: Clifford WoolfSomatosensory control of barrier tissue immunity


Rockefeller University
Sponsor: Seth A DarstMechanism of transcription activiation


University of California, Los Angeles
Sponsor: Sriram KosuriDeep mutational suppressor screens to uncover splicing mechanisms and coding constraints


University of California, San Francisco
Sponsor: Harold E VarmusConstruction of hormone modulated transformed cells


Stanford University
Sponsor: Eugene C ButcherHoming mechanisms of normal and malignant lymphocytes


University of Wisconsin, Madison
Sponsor: Elizabeth A CraigMultiple protein tyrosine phosphatase genes from the yeast S. cerevisiae


University of California, San Francisco
Sponsor: Ronald ValeDefining the role of the actin cytoskeleton in plasma membrane organization during T-cell activation


Yale University
Sponsor: Joseph G GallGene expression


Stanford University
Sponsor: K. Christopher GarciaElucidating the molecular basis of canonical Wnt signaling activation and inhibition at the cell surface


Stanford University
Sponsor: Paul BergHomologous recombination in mammalian cells


University of California, Berkeley
Sponsor: I Tinoco, JrInteractions of proteins with nucleic acids


Montefiore Hospital
Sponsor: Theodore H SpaetMetabolism of hemoglobin


Columbia University
Sponsor: James E Darnell, JrIncorporation of adenovirus into the host DNA of transformed cells


Cold Spring Harbor Laboratory
Sponsor: R F. GestelandSV40 DNA and SV40 messenger RNA


Columbia University
Sponsor: Saeed TavazoieMicrobial adaptation to extreme environments facilitated by CRISPR-Cas


Massachusetts Institute of Technology
Sponsor: H Robert HorvitzNeuronal cell differentiation


University of California, San Francisco
Sponsor: Douglas HanahanAP-1 factors in mouse models of tumorigenesis


Rockefeller University
Sponsor: Vincent AllfreyChromosome structure


Albert Einstein College of Medicine
Sponsor: J Thomas AugustRole of protein phosphorylation in tumor virus infection


University of California, San Francisco
Sponsor: Graeme DavisMechanisms of VCP-mediated cellular degeneration


Rockefeller University
Sponsor: Jue ChenStructural and mechanistic studies of multidrug resistance mediated by MRP1


California Institute of Technology
Sponsor: John N AbelsonYeast mRNA splicing


New York University
Sponsor: Claude DesplanStochastic fate choice generating the retinal mosaic


University of California, Berkeley
Sponsor: Jeremy ThornerYeast mating pheromones: their mechanism of action


Harvard University Medical School
Sponsor: Marc W KirschnerVertebrate growth control in a developmental context


California Institute of Technology
Sponsor: Douglas C ReesGAL6-A DNA-binding protease


New York University
Sponsor: Alexander F SchierRole of nodal signaling during gastrulation


Harvard University
Sponsor: Hopi HoekstraGenetic and neural basis of natural variation in infant vocalization


Columbia University
Sponsor: Richard AxelApproaches to isolating a gene encoding a mammalian serotonin receptor


Yale University
Sponsor: Peter NovickRole of a Ras-like protein in yeast secretion

National Jewish Center for Immunology and Respiratory Medicine
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National Jewish Center for Immunology and Respiratory Medicine
Sponsor: Gordon M KellerRole of c-rel in development and gene expression


Harvard University
Sponsor: Matthew MeselsonStructure of ribosomes


Stanford University
Sponsor: Michael Bassik and Tony Wyss-CorayMechanistic dissection of mTOR and autophagy gene function in phagocytosis

Imperial Cancer Research Fund Laboratories, England
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Imperial Cancer Research Fund Laboratories, England
Sponsor: Renato DulbeccoTransformation of human diploid fibroblasts by chemical carcinogens


University of California, San Francisco
Sponsor: Jonathan WeissmanGenetic interaction mapping and mechanisms of human host cell pathways exploited by endoplasmic reticulum-trafficking toxins


Yale University
Sponsor: Thomas A SteitzCrystallographic studies of DNA-resolvase complexes


University of California, Berkeley
Sponsor: Nicholas R CozzarelliDevelopment of a cell-free general recombination system


Brigham and Women's Hospital
Sponsor: STEPHEN J ElledgeElucidation of senescence regulatory networks using unbiased genetic screens


La Jolla Institute for Allergy and Immunology
Sponsor: Anjana RaoThe roles of TETs in pluripotency and early embryogenesis


Harvard University
Sponsor: Catherine DulacFunctional development of social behavior circuits


Stanford University
Sponsor: A. Dale KaiserDevelopmental regulation of an A-factor-dependent gene in Myxococcus


Massachusetts Institute of Technology
Sponsor: H Robert HorvitzMechanosensory cell function in C. elegans


MD Anderson Cancer Center
Sponsor: Ronald DePinhoDelineate mechanisms of oncogenic KRAS independent effector pathways of pancreatic cancer


University of California, San Diego
Sponsor: Samara Reck-PetersonCellular regulation of cargo motility


Memorial Hospital, New York
Sponsor: C P RhoadsCancer chemotherapy


University of Cambridge, England
Sponsor: Michael AshburnerMolecular cloning of the Adh locus of D. melanogaster


University of California, San Francisco
Sponsor: Bruce M AlbertsOrganization of the cell cytoplasm


Indiana University
Sponsor: Anthony MahowaldNuclear proteins of Drosophila pole cells


Stanford University
Sponsor: Hunter Fraser and Andrew FireVariation in chromosomal interactions in 10 human populations


University of California, San Francisco
Sponsor: Frank LorenNeural activity underlying individual variability in spatial decisions


Rockefeller University
Sponsor: Cori BargmannFunctional maturation of the nervous system in the nematode C. elegans


Yale University
Sponsor: William KonigsbergStructure of the coat protein of the f2 phage of E. coli


Massachusetts Institute of Technology
Sponsor: Alexander RichAmino acid sequence of myeloma immunoglobulins


California Institute of Technology
Sponsor: Seymour BenzerGenetic dissection of the neuromuscular junction


Stanford University
Sponsor: Liqun LuoInvestigating cell type and brain circuit evolution in the cerebellum


Harvard University
Sponsor: James WangStructure and function of the RecQ helilcase


Yale University
Sponsor: Mark BitenskyRole of adenyl cyclase in the excitation of vertebrate photoreceptors


Harvard University Medical School
Sponsor: Gerhard WagnerInteraction of cyclophilin, CsA and calcineurin


Universite de Geneve, Switzerland
Sponsor: E KellenbergerUltrastructural behavior of chromosomes


University of Pennsylvania
Sponsor: Mark A. LemmonInvestigating dynamin as a model for functionality important low-affinity PH domain/phosphoinositide interactions


Albert Einstein College of Medicine
Sponsor: M J OsbornBiosynthesis of bacterial lipopolysaccharides


MRC Center, University Medical School, England
Sponsor: Sydney BrennerDevelopment of genetic mosaic analysis in C. elegans


Harvard University
Sponsor: Douglas MeltonGrowth factor-regulated effectors of pattern formation

Ludwig Institute for Cancer Research
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Ludwig Institute for Cancer Research
Sponsor: Karen OegemaMechanics of contractile ring constriction


Harvard University Medical School
Sponsor: Norbert Perrimon

University of California, Berkeley
Sponsor: Judith KlinmanThermophilic reductase dynamics and nuclear tunneling


Boston Children's Hospital
Sponsor: Michael GreenbergSignaling pathway by L type Ca2+ channel


Whitehead Institute for Biomedical Research
Sponsor: David BaltimoreB cell differentiation


Johns Hopkins University
Sponsor: Solomon SnyderThe role for nuclear GAPDH in the regulation of p300/p53 activation


Salk Institute for Biological Studies
Sponsor: Andrew DillinStudy of relationship between metabolism and protein homeostasis in neurodegenerative diseases, with Andrew Dillin


MRC Center, University Medical School, England
Sponsor: John SulstonCell determination during organogenesis in C elegans


University of California, San Francisco
Sponsor: Cornelia E BargmannIsolation and characterization of a C elegans mutation


MRC Center, University Medical School, England
Sponsor: Aaron KlugProteins of the sheath of bacteriophage T4 and the capsid structure of animal viruses


Massachusetts Institute of Technology
Sponsor: Phillip A SharpDeletion mapping of adenovirus 5 region E1B


University of California, Berkeley
Sponsor: W P JencksOrganic chemistry models for enzyme reactions


University of California, San Francisco
Sponsor: Harold E VarmusCharacterization and purification of int-1 and proteins expressed from baculovirus vectors


University of California, San Francisco
Sponsor: Yuh Nung JanFunctional assembly of a cardiac reflex circuit


Salk Institute for Biological Studies
Sponsor: Robert HolleySerum factor requirements of differentiated mammalian cells cultured in vitro


Karolinska Institutet, Sweden
Sponsor: Klein, GeorgeInvestigations concerning cell growth, survival and destruction in a transplantation situation


Stanford University
Sponsor: Gerald R CrabtreeRegulation of NF-ATc nuclear translocation


Sidney Farber Cancer Center
Sponsor: Arthur PardeeRegulation of cell growth


Salk Institute for Biological Studies
Sponsor: Ronald M EvansTranscriptional repression by the c-erbA product


Stanford University
Sponsor: Charles YanofskyDNA protein interactions


Columbia University
Sponsor: Argiris Efstratiadis

University of Chicago
Sponsor: Bernard RoizmanRegulation of synthesis of herpesvirus gene products


Fred Hutchinson Cancer Center
Sponsor: Robert N EisenmanAnalysis of Mga, a novel member of the Max network


University of California, Berkeley
Sponsor: Randy W SchekmanCharacterization and localization of the SEC7 protein


University of California, San Francisco
Sponsor: Bruce M AlbertsRecombination and DNA replication in phage T4


Yale University
Sponsor: Antonio GiraldezDissecting the molecular mechanisms that trigger zygotic genome activation


Purdue University
Sponsor: Michael G RossmannVirus receptor interactions on a molecular level


Whitehead Institute
Sponsor: Michael Lisanti & David BaltimoreA loss of caveolae/caveolin in transformed cells

University of California, San Francisco
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University of California, San Francisco
Sponsor: Hiten MadhaniInvestigation of the role of chromatin dynamics in programming gene expression noise


Rockefeller University
Sponsor: John KuriyanExpression, purification and x-ray study of src kinase


Massachusetts Institute of Technology
Sponsor: Phillip A SharpRNA splicing in eukaryotic cell free systems


Stanford University
Sponsor: I Robert LehmanEnzymatic characterization of E coli mutants


Johns Hopkins University
Sponsor: Leroy F. LiuEffects of DNA bending stress on DNA structure and function


Fred Hutchinson Cancer Center
Sponsor: Harold WintraubMouse Notch


University of California, Berkeley
Sponsor: Corey S. GoodmanMutations affecting axon outgrowth in the developing nervous system of D melanogaster


University of California, San Francisco
Sponsor: Peter WalterTaking apart a molecular switch: structure, regulation and specificity of the bifunctional kinase-ribonuclease IRE1


Fred Hutchinson Cancer Center
Sponsor: Mark GroudineNuclear reorganization during erythrocyte development


Harvard University
Sponsor: James C WangLambda intergrase


Massachusetts Institute of Technology
Sponsor: Phillips W RobbinsSubcellular localization of glycolipid changes during viral transformation


Rockefeller University
Sponsor: Moses KunitzPurification and crystallization of enzymes and proteins


Stanford University
Sponsor: Ronald W. DavisRNA synthesis from fragments of eukaryotic genomes


Yale University
Sponsor: Samuel C HarveyTumors of neural origin


Massachusetts Institute of Technology
Sponsor: Phillip A SharpRepression of enhancer activity by adenovirus E1A


New York University
Sponsor: Severo OchoaInfluence of DNA on synthesis of RNA


Cold Spring Harbor Laboratory
Sponsor: Leemor Joshua-TorRabGDI displacement factors: mechanism and function in membrane traffic


Stanford University
Sponsor: A. Dale Kaiser & Frank StahlEnzyme recognition of base sequences on DNA


Case Western Reserve University


Stanford University
Sponsor: Elaine FuchsCentrosomes and the regulation of asymmetric cell division


University of California, San Francisco
Sponsor: Jeremy ReiterCentriolar satellites use phase separation to remodel the centrosome


MRC Center, University Medical School, England
Sponsor: Aaron KlugCloning and crystallization of TFIIIA Zn-binding domains


Massachusetts Institute of Technology
Sponsor: David BaltimoreRole of terminal deoxynucleotidyl transferase in developing thymus


California Institute of Technology
Sponsor: David J. AndersonGenetic dissection of amygdala neuronal circuitry underlying fear and anxiety in mice


Harvard University
Sponsor: William N LipscombCatalysis and regulation of ornithine transcarbamylase


Washington University in St. Louis
Sponsor: Michael P SheetzMicrotubule-dependent motility of organelles

Whitehead Institute for Biomedical Research
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Whitehead Institute for Biomedical Research
Sponsor: Robert A WeinbergInduction of mammary tumor by p-53-deficient stroma


National Institutes of Health
Sponsor: Herman M KalckarFormation and metabolism of nucleoside pholyphosphate


Stanford University
Sponsor: Kang ShenA search for determinants of synaptic size and function


Columbia University
Sponsor: Rodney J RothsteinGenetic control of recombination in yeast


Harvard University
Sponsor: Xiaowei ZhuangSuperresolution imaging of age related changes to the neuronal cytoskeleton


Sloan Kettering Institute for Cancer Research
Sponsor: Kathryn AndersonGenetic approaches to primordial germ cell migration


Brigham and Women's Hospital
Current Sponsor: Matthew WaldorAwarded Sponsor: Brigham and Women's Hospital
Polarity and pathogenesis: identification and characterization of cell polarity determinants in Vibrio cholerae


Albert Einstein College of Medicine
Sponsor: Julius MarmurYeast mitochondrial nucleic acid metabolism


Columbia University
Sponsor: Aaron P MitchellMeiotic DNA synthesis and control of meiosis in yeast


University of California, Berkeley
Sponsor: John KuriyanDNA pol III holoenzyme structure determination


Stanford University
Sponsor: Paul BergIsolation and characterization of integrated SV40 DNA


University of California, Berkeley
Sponsor: Esmond E SnellStructure and function of histidine decarboxylase


Stanford University
Sponsor: Stephen M BlockMicromechanics of kinesin movement


MRC Center, University Medical School, England
Sponsor: A Klug and H HuxleyLocalization of chemical sites in biological electron microscopy


Harvard University Medical School
Sponsor: Stephen C HarrisonRegulation of kinetechore assembly


University of California, San Francisco
Sponsor: Marshall WallacePrinciples of cellular behavior: gait coordination in unicellular walker

Imperial Cancer Research Fund Laboratories, England
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Imperial Cancer Research Fund Laboratories, England
Sponsor: Tomas LindahlDNA ligase 1


Fred Hutchinson Cancer Center
Sponsor: Harold WeintraubFine mapping the hypersensitive sites in globin genes


Massachusetts Institute of Technology
Sponsor: Francis O SchmittCellular ultrastructure and function


University of Edinburgh, Scotland
Sponsor: David FinneganIsolation of the gene polycomb of Drosophila


University of California, San Francisco
Sponsor: Peter WalterStructure/function analysis of the SRP receptor


University of California, San Francisco
Sponsor: Peter WalterDynamic control of the integrated stress response by elF2B


University of Cambridge, England
Sponsor: Ernest D LaueProtein-protein interactions in cell cycle regulation


Harvard University
Sponsor: Emily BalskusCharacertization of catechol dehydroxyglases in the gut microbiome


Boston Children's Hospital
Sponsor: Judy LiebermanThe role of secreted mircroRNA's in breast cancer metastasis


California Institute of Technology
Sponsor: David J AndersonRole of Mrg receptors in perception of pain


Rockefeller University
Sponsor: Elaine FuchsE cadherin function in epidermal cell adhesion


Yale University
Sponsor: E L Tatum and Francis J RyanGenetic aspects of growth


University of Stockholm, Sweden
Sponsor: Lars ErnsterMechanism of energy conservation in mitochondria


Harvard University Medical School
Sponsor: Charles ThomasReplication of viral DNA


Massachusetts General Hospital
Sponsor: Frederick M AusebelMechanisms of P aeruginosa toxin-mediated killing


Rockefeller University
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University of Illinois at Urbana-Champaign
Sponsor: Taekjip HaA single molecular study of the exosome to understand the RNA 3'-5" processing, degradation, and polymerization


Yale University
Sponsor: Elisabetta Ullu and Christian TschudiMechanism for translational regulation of HMG CoA reductase


Harvard University Medical School
Sponsor: Jonathan R BeckwithProtein secretion in E. coli


Harvard University
Sponsor: Michael GreenRegulation of adenovirus pre-mRNA splicing


University of California, San Francisco
Sponsor: Harold E VarmusGenetic screen to identify factors that interact with mRNA pseudoknot in -1 ribosomal frameshifting


Princeton University
Sponsor: Jeffry B StockMembrane targeting of ras proteins


Rockefeller University
Sponsor: Roderick MacKinnonStructural and mechanistic principles of the HCN pacemaker channel


Massachusetts Institute of Technology
Sponsor: Harvey LodishOrganization of repetitive DNA in Dictyostelium


Rockefeller University
Sponsor: H D RobertsonDouble-stranded RNA


Harvard University
Sponsor: Charles A Thomas, Jr. and H. DotyOrganization of chromosomal DNA


University of Texas
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Johns Hopkins University
Sponsor: Victor G CorcesRNAi and gypsy insulator in chromatin organization


University of California, Berkeley
Sponsor: Kristin ScottMaturation of neural circuits for memory

University of California, San Francisco
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University of California, San Francisco
Sponsor: David JuliusUsing unique crocodilian physiology to probe somatosensation


Massachusetts Institute of Technology
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University of California, San Francisco
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University of California, San Francisco
Sponsor: Jonathan WeissmanUnderstanding sphingolipid homeostasis in human cells: function and regulation of ORMDL proteins


University of California, Berkeley
Sponsor: Eva Nogales

Princeton University
Sponsor: S. Tilghman and S. WassermanPhenotypic cloning of PC13 differentiation genes


University of Oxford, England
Sponsor: K. BurtonIncrease our understanding of cell growth, deelopment, and differentiation


University of Basel, Switzerland
Sponsor: Walter GehringCharacterization of the Drosophila doublesex locus


National Cancer Institute
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California Institute of Technology
Sponsor: Douglas D ReesX-ray crystallography of multidrug transporters


Scripps Research Institute
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Stanford University
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Rockefeller University
Sponsor: Michael YoungDecoding neuromodulatory control of sleep and wakefulness in Drosophila


Stanford University
Sponsor: Mark DavisMapping Global and TCR-Vicinity proteomic states of T Lymphocyte Surface


Harvard University Medical School
Sponsor: Christopher T WalshUnusual redox chemistry in the biosynthesis and action of the dithiolopyrrolone natural product holomycin


University of Massachusetts Medical School
Sponsor: Phillip ZamoreUnderstanding the function and regulation of piRNAs in mammals


Harvard University Medical School
Sponsor: Timothy MitchisonTarget cancer with chemical genetics


Rockefeller University
Sponsor: Elaine FuchsDissecting the molecular crosstalk that governs melanocyte stem cells in their niche


Massachusetts General Hospital
Sponsor: Bradley BernsteinActivity-based profiling of lysine-specific demethylase 1


Duke University
Sponsor: Philip BenfeyCell-type specific growth regulation in response to cross-kingdom communication


Rockefeller University
Sponsor: Elaine FuchsUnraveling the complexities of Wnt signaling in stem cell activation, wound repair and tumorigenesis in the skin


University of California, San Francisco
Sponsor: Anatol KreitzerContribution of basal ganglia-recipient thalamus to cortical motor plans


Yale University
Sponsor: Ruslan MedzhitovDeciphering the mechanism and significance of stress tolerance


Massachusetts Institute of Technology
Sponsor: Michael B YaffeCharacterization of the Pik1 polo-box domain


University of California, Berkeley
Sponsor: Corey S GoodmanExpression cloning of Beaten Path receptor


Harvard University Medical School
Sponsor: Christopher T WalshA chemoenzymatic approach to novel antibiotics


Carnegie Institute for Science
Sponsor: Allan C SpradlingGenetic analysis of Drosophila oocyte determination


University of California, San Diego
Sponsor: Roger Y TsienNovel tools for studying neuronal cadherin function


California Institute of Technology
Sponsor: David J. AndersonNeural substrates underlying aggressive vs. sexual behavior in mice

Imperial Cancer Research Fund Laboratories, England
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Imperial Cancer Research Fund Laboratories, England


University of Washington, Seattle
Sponsor: Peter VogtViral nucleic acid in cells transformed by avian tumor viruses


Yale University
Sponsor: G R WyattAction of growth substances in insect tissues


University of California, San Francisco
Sponsor: Kevan ShokatA chemical genetics approach on how signaling controls aberrant mRNA splicing in cancer

Centre Nationale de la Recherche Scientifique, France
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Centre Nationale de la Recherche Scientifique, France
Sponsor: Boris EphrussiGenetic control of the synthesis of respiratory enzymes in yeast

Centre Nationale de la Recherche Scientifique, France
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Centre Nationale de la Recherche Scientifique, France
Sponsor: J P NitschMetabolic effects induced in various plant cells


Stanford University
Sponsor: George R StarkCellular mechanism for control of protein synthesis


Scripps Research Institute
Sponsor: Claire Waterman-StorerIntegrative cytoskeletal model for cell motility


Columbia University
Sponsor: Richard AxelGene transfer


Memorial Sloan-Kettering Cancer Center
Sponsor: Joan MassagueIdentification and cloning of TGF-beta receptor interacting proteins


Rockefeller University
Sponsor: Elaine FuchsExploring the mechanism of skin stem cell regulation in skin wound repairs


Stanford University
Sponsor: Joanna WysockaPrion dynamics of transcription factors control cellular differentiation


Harvard University
Sponsor: Catherine DulacNeural control of social motivation


California Institute of Technology
Sponsor: Grant JensenIn vivo structure and function of the H. pylori cag type IV secretion system


Stanford University School of Medicine
Sponsor: Roger KornbergStructural, biochemical and genetic studies of the role of the trigger loop in substrate specificity and catalysis in RNA polymerase II transcription


Stanford University
Sponsor: Kang ShenImmunoglobulin-domain proteins and synaptic specificity


California Institute of Technology
Sponsor: Raymond DeshaiesRegulation of cullin-RING ubiquitin ligases by Cand!


Whitehead Institute for Biomedical Research
Sponsor: Gerald R FinkNew targeting pathway in yeast


Carnegie Institute for Science
Sponsor: Donald D BrownRNA transcription


University of California, San Francisco
Sponsor: Arthur WeissThe role of T cell receptor-induced sulfenylation in CD4+ T cell differentiation


Massachusetts Institute of Technology
Sponsor: U L RajBhandarySequencing of hemoglobin mRNA


Columbia University
Sponsor: Lucille ShapiroDevelopmental regulation of membrane biogenesis


National Institutes of Health
Sponsor: M SingerDegradation of mRNA in E. coli


Stanford University
Sponsor: L A HerzenbergPhysical and functional characteristics of purified populations of lymphocytes from mice


California Institute of Technology
Sponsor: Dianne NewmanBacterial nitric oxide metabolism at the host-pathogen interface


California Institute of Technology
Sponsor: Jacqueline K BartonOn demonstrating DNA intercalation


Harvard University Medical School
Sponsor: Antoine van OijenSingle-molecule enzymology of the replisome

Vanderbilt University Medical Center
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Vanderbilt University Medical Center
Sponsor: Eric SkaarDefining the clostridium difficile responses to zinc limitation


Carnegie Institute for Science
Sponsor: Allan SpradlingDrosophila melanogaster spermatheca: a new model for the prostate gland


MD Anderson Cancer Center
Sponsor: Ronald DePinhoGenetic and genomic analysis of prostate cancer progression


Harvard University Medical School
Sponsor: Joan S BruggeIdentifiction of migration genes from breast cancer


Massachusetts Institute of Technology
Sponsor: Francis O SchmittCell membranes


Stanford University
Sponsor: Eric Shooter and Leslie WilsonSequencing of chick brain microtubule protein


California Institute of Technology
Sponsor: Ellen RothenbergImmunological analysis of thymus gland lymphocytes


University of Chicago
Sponsor: Paul B Siglertrp repressor/operator system: structure and function


Yale University
Sponsor: Harry S N GreeneHeterologous transplantation of human tumors


University of California, San Francisco
Sponsor: Yuh Nung JanGenetic dissection of neuronal morphogenesis


Massachusetts Institute of Technology
Sponsor: Daniel NoceraIdentification of transient reactive intermediates in RNR's and potential role in therapeutics


University of California, San Francisco
Sponsor: David A AgardMechanism of microtubule nucleation in the centrosome


University of California, Berkeley
Sponsor: Daniel E Koshland, JrTransmembrane regions of the E coli aspartate receptor


University of Colorado, Boulder
Sponsor: Thomas R CechRegulation of telomere binding protein activity


Harvard University Medical School
Sponsor: Constance CepkoGenes encoding bHLH proteins in the mouse retina


University of Washington
Sponsor: Wenqing XuStructural study of porcupine, a membrane protein essential to Wnt function


New York University
Sponsor: Jerard HurwitzNucleic acid synthesis


University of Copenhagen, Denmark
Sponsor: O MaaloeControl mechanisms of cell growth


Rockefeller University
Sponsor: E L TatumMechanisms of synthesis of polypeptides in bacteria


Rockefeller University
Sponsor: Titia de LangeCan telomere attrition initiate chromosome shattering?


Massachusetts Institute of Technology
Sponsor: Jaqueline Lees

University of Utah
Sponsor: Michael ShapiroUncovering the genetic basis of variation in musculoskeletal patterning

University of California, San Diego
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University of California, San Diego
Sponsor: Charles ZukerMolecular characterization of gustatory labeled lines


University of California, San Francisco
Sponsor: Ron D Vale and Larry GeraceIdentification of signals for vectorial export of macromolecules from the nucleus


Sloan Kettering Institute for Cancer Research
Sponsor: James RothmanIdentification and characterization of golgi SNARE complexes


University of California, San Francisco
Sponsor: Charles EpsteinMechanism of regulation of gene expression in eukaryotic cells


Albert Einstein College of Medicine
Sponsor: Jerard HurwitzInitiation and termination of transcription by RNA polymerases


University of California, San Francisco
Sponsor: Harold E VarmusMouse mammary tumor virus DNA from infected HTC cells


Stanford University
Sponsor: Nadav AhituvUntangling the locus coeruleus noradrenergic neural circuit


Institut Pasteur, France
Sponsor: J MonodGenetic control systems


MD Anderson Cancer Center
Sponsor: Sean PosthnRNP K: a putative driver of high risk DLBCL


Lymphoma Treatment Centre, Uganda
Sponsor: John L ZieglerDiagnostic and treatment procedures


Memorial Sloan-Kettering Cancer Center
Sponsor: Scott LoweBiological impact of chromosome deletions on tumorigenesis


California Institute of Technology
Sponsor: Norman DavidsonIntegration of DNA from SV40


Biocentrism der Universitat, Switzerland
Sponsor: J.P. Rosenbusch and Jonathan R BeckwithMembrane components involved in E coli conjugation


Stanford University
Sponsor: Paul BergCloning of human low density lipoprotein gene(s)


Harvard University
Sponsor: Fotis C KafatosTemporal specificity of chorion gene expression in Drosophila

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Alan C StevensonMedical genetics


Rockefeller University
Sponsor: Eugene L OpieHistochemical study of precancerous lesions


University of California, Los Angeles
Sponsor: Douglas L Black, Doulas L BlackStructure of a neuronal splicing enhancer complex


Harvard University Medical School
Sponsor: Norbert PerrimonWhole-genome RNAi screens to dientify insulator genes


Massachusetts Institute of Technology
Sponsor: Stephen J LippardPlatinum oligonucleotides and anticancer drugs


Northwestern University
Sponsor: Eric J. SontheimerMechanisms of sequence-based resistance to bacteriophages and plasmids in Eubacteria


Carnegie Institute for Science
Sponsor: Donald D BrownXenopus functional assay for the study of apoptosis


Johns Hopkins University
Sponsor: Katherine L WilsonRegulation of nuclear envelope assembly after mitosis


University of North Carolina
Sponsor: Marshall H EdgellEmbryo microinjection


Harvard University
Sponsor: Michael R GreenMechanisms used by eukaryotic transcriptional activator proteins


University of California, Berkeley
Sponsor: Harry RubinCell transformation


Yale University
Sponsor: Wendy GilbertDefining the landscape and function of pseudouridines in pre-mRNA


La Jolla Institute for Allergy and Immunology
Sponsor: Patrick HoganInduction of anergy/exhaustion by NFAT1


University of California, Berkeley
Sponsor: Wendell M StanleyMouse leukemia


Harvard University
Sponsor: Charles C RichardsonT7 DNA replication in vitro


Harvard University Medical School


University of California, San Diego
Sponsor: Joseph KrautStructure determination of the enzyme dihydrofolate reductase


Rockefeller University
Sponsor: Leslie VosshallMolecular genetics of water sensation and oviposition site preference the in the yellow fever mosquito


University of Wisconsin, Madison
Sponsor: Howard M TeminTumor viruses


Stanford University
Sponsor: Howard M TeminInteraction of the lac-repressor protein with DNA


Pennsylvania State University
Sponsor: Stephen J BenkovicHelicase dynamics in DNA replication


Massachusetts Institute of Technology
Sponsor: Peter K. Sorger

University of California, San Francisco
Sponsor: Ronald D. ValeKinesin's biological roles, a genetic approach

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Frances Crick and Sydney BrennerStructure and function in tRNA


Stanford University
Sponsor: I R LehmanEnzymatic analysis of general recombination


Harvard University Medical School
Sponsor: Jonathan R BeckwithRNA transcrption


University of California, Los Angeles
Sponsor: Walter J GehringIsolation of Drosophila genes


Stanford University
Sponsor: Peter Parham & Irving L WeissmanDifferentiation of T cells initiated by stimulation of the R cell antigen receptor


California Institute of Technology
Sponsor: Robert M Stroud & Thomas A SteitzHuman thrombin, lactose repressor system


University of California, San Diego
Sponsor: Dan L LindsleyRole of x heterochromatin in control of meiosis and spermatogenesis in D. melanogaster


Weizmann Institute of Science, Israel
Sponsor: Nathan SharonMechanism of enzymatic action of lysozyme


University of California, Berkeley
Sponsor: Jeremy W ThornerAnalysis of septin filament assembly in S. Cerevisiae


University of Copenhagen, Denmark
Sponsor: Herman Kalckar & E Hoff JorgensenNucleic acids


Harvard University
Sponsor: Susan MangoThe role of PHA-4 binding in cell fate specification during organ formation


Stanford University
Sponsor: Chaitan KhoslaBiosynthetic engineering of a polyketide synthase


Harvard University Medical School
Sponsor: Gerhard WagnerNMR studies of human dihydrofolate reductase


Massachusetts General Hospital
Sponsor: Gary Ruvkun and Vamsi MoothaMolecular mechanisms of oxygen sensation and mitochondrial dysfunction


Massachusetts General Hospital
Sponsor: Gary RuvkunRegulation of energy homeostatis in C. elegans


Brigham and Women's Hospital
Sponsor: Stephen J ElledgeDefining nuclear-specific degradation pathways


University of Cambridge, England
Sponsor: J S MitchellBiological effects of irradiation


University of California, Santa Barbara
Sponsor: Steven I ReedRegulation of CDC28 kinase activity


Harvard University Medical School
Sponsor: Alexander SchierGeneration of hypocretin Neurons from narcoleptic patients


Institut Pasteur, France
Sponsor: Y Hirota & F GrosMembrane synthesis, cell growth and division


Stanford University
Sponsor: Paul Berg, J. Gurdon and Mary Lou PardueIdentification and genomic mapping of SV40-coded polypeptides


New York University
Sponsor: Dan LittmanUncovering the role of the inflammatory response in digit tip regeneration


University of California, San Francisco
Sponsor: Michael BrainardIdentification of genetic constituents of learning in songbirds through a new system for molecular marker development


Harvard University Medical School
Sponsor: Johannes WaltersMechanism of transcription-coupled DNA interstrand cross-link repair


Stanford University
Sponsor: David S HognessSteroid-responsive genes of Drosophila


Rockefeller University
Sponsor: Elaine FuchsDissecting the immune evasion mechanisms of tumorigenic stem cells


University of California, San Francisco
Sponsor: Keith R YamamotoModulation of gene expression by regulatory proteins


Scripps Research Institute
Sponsor: James R. WilliamsonKinetic analysis of 30S ribosomal subunit assembly


Massachusetts Institute of Technology
Sponsor: Robert T SauerProtein folding information in the Arc repressor


Harvard University
Sponsor: Mark PtashneBiochemistry of cell type control in yeast


Harvard University Medical School
Sponsor: Timothy MitchisonChemical inhibition of microtubule nucleation


University of California, Berkeley
Sponsor: Randy SchekmanIn vitro reconstitution of golgi biogenesis in S. cerivisiae


Stanford University School of Medicine
Sponsor: David KingsleyDevelopmental genetics of stickleback raker number


Cold Spring Harbor Laboratory
Sponsor: Bruce StillmanRegulation of eukaryotic DNA replication


Rockefeller University
Sponsor: E L TatumMechanism of suppression or rg mutant in Neurospora


California Institute of Technology
Sponsor: David ChanRegulation of mitochondrial fusion


University of California, San Francisco
Sponsor: Marc Tessier-LavigneA screen for axon guidance molecules in mouse

University of California, Berkeley
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University of California, Berkeley
Sponsor: Vance RussellPathogen-driven evolution of inflammasome genes


Yale University
Sponsor: Donald M CrothersDNA topology in viruses


Yale University
Sponsor: Joan A. Steitz

University of California, San Diego
Sponsor: Massimo ScanziaTop-down modulation of visual cortex during attention


Yale University
Sponsor: William U GardnerStructure and hormonal responses of mammary glands of embryonic components


Rockefeller University
Sponsor: Luciano MarraffiniSelf vs. non-self discrimination during CRISPR-Cas adaptive immunity

University of California, Berkeley
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University of California, Berkeley
Sponsor: Andrew DillinIntra and trans-cellular mitochondrial communication in Parkinson's disease


Harvard University
Sponsor: Catherine DulacNeuronal control of suckling behavior in newborn rodents


University of Oregon
Sponsor: Tom H StevensIn vitro assay for Golgi to vacuole transport utilizing all yeast components


Rockefeller University
Sponsor: Robert DarnellDefining layers of post-transcriptional control in chronic inflammatory disease


University of Utah
Sponsor: Jared RutterThe eukaryotic RNA-metabolite interactome and its role in gene regulation


Yale University
Sponsor: Joan A SteitzPrimer recognition properties of the human telomere terminal transferase enzyme


University of Connecticut Health Center
Sponsor: S E PfeifferSurfaces of cells of nervous tissues


University of California, San Francisco
Sponsor: Adam FrostStructural studies of membrane fission and highly constricted membranes


Harvard University Medical School
Sponsor: John A T YoungMolecular mechanism of retroviral fusion


University of California, Berkeley
Sponsor: Sung-Hou Kim & Daniel E KoshlandX-ray crystallographic studies of chemotaxis receptors


University of California, Davis
Sponsor: P K StumpfBiosynthesis of unsaturated fatty acids


Harvard University
Sponsor: Sunney Xiaoliang XieLive cell imaging of chromatin supercoiling dynamics in human cells


Johns Hopkins University
Sponsor: Thomas D PollardBiochemistry of a cortical proilin binding complex


University of Dundee, Scotland
Sponsor: Graham WarrenMechanisms of Golgi-fragmentation during mitosis


Princeton University
Sponsor: Arnold J Levinep53 negatively regulates a microtubule-associated protein


Yale University
Sponsor: Harry S N GreeneHeterologous transplantation of human tumors


University of Washington
Sponsor: Robert H WaterstonEmbryonic single-cell gene expression in C. elegans


Harvard University
Sponsor: Fotis C KafotisNotch, a regulator of neural determination in D. Melanogaster


Johns Hopkins University
Sponsor: Deborah AndrewTubulogenesis during Sriosophila embryonic development


University of Wisconsin, Madison
Sponsor: Robert L MetzenbergIsolation of the tol+ gene from Neurospora crassa


Yale University
Sponsor: William U GardnerNature of the reticulum cell and anaplastic types


Stanford University
Sponsor: I R Lehman & John LittlefieldEnzymatic basis of recombination


Albert Einstein College of Medicine
Sponsor: Jerard HurwitzRNA synthesis


University of Washington
Sponsor: Benjamin D HallControl of transciption in yeast


University of California, San Francisco
Sponsor: Peter WalterStudy of mechanisms ensuring productive SRP targeting


University of California, Los Angeles
Sponsor: Virginia L ScofieldCell-cell recognition

National Institute of Allergy and Infectious Diseases
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National Institute of Allergy and Infectious Diseases
Sponsor: William E PaulMolecular interactions in the IL-4 receptor signaling pathway

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Aaron KlugMutagenic analysis of nucleosome postioning


Pennsylvania State University
Sponsor: Stephen J BenkovicKinetics and mechanism of lesion bypass


Broad Institute
Sponsor: David LiuContinual evolution of proteins in eukaryotes


Fred Hutchinson Cancer Center
Sponsor: Robert EisenmanModeling Myc-induced tumorigenesis in Drosophila


Rockefeller University
Sponsor: James E Darnell JrMessenger RNA


Albert Einstein College of Medicine
Sponsor: Barry BloomProperties of products of activated lymphocytes


Yale University
Sponsor: Harr S N GreeneHeterologous transplantation of tumors


University of California, San Francisco
Sponsor: Anita SilKey regulators of pathogenesis in H capsulatum


Columbia University
Sponsor: Councilman MorganElectron microscopy


University of California, San Francisco
Sponsor: Peter WalterRNA function in the signal recognition particle


University of California, San Francisco
Sponsor: John D BaxterGene Expression


Harvard University
Sponsor: Elizabeth RobertsonAnalysis of the control of nodal expression


Albert Einstein College of Medicine
Sponsor: Jerard HurwitzDNA dependent RNA polymerase


Yale University
Sponsor: Richard FlavellInflammasome dysregulation in colorectal tumorigenesis


University of Wisconsin, Madison
Sponsor: Barry GanetzkyNeurogenetics of synaptic growth and plasticity


University of California, San Francisco
Sponsor: G Tompkins & W J RutterSegregation of chromosomal proteins


University of California, San Francisco
Sponsor: Erin K O'Shea, Erin O'SheaRegulation of the activity of the CDK inhibitor PHO81


University of California, San Francisco
Sponsor: Thomas B Kornberg & Mark A TanouyeTranscriptional regulation of the engrailed gene


University of California, Berkeley
Sponsor: Michael RapeInvestigating the ubiquitin-dependent mechanisms that govern human stem cell maintenance and the course of neurogenesis


Harvard University Medical School
Sponsor: Thomas WalzElectron microscopy of spliceosomes


Stanford University
Sponsor: Paul BergExpression of cDNAs in mammalian cells


Harvard University
Sponsor: Tom ManiatisCloning and analysis of trans-acting factors controlling Drosophila adult Adh expression


Stanford University
Sponsor: Bruce BakerFruitfly splicing mutations


University of California, San Francisco
Sponsor: Yuh-Nung JanModes of microtubule nucleation in Drosophila neurons


University of California, San Diego
Sponsor: Gordon H SatoHormonal regulation of ovarian cell cycle in culture


National Institutes of Health
Sponsor: Peter T MoraViral oncogenesis


Carnegie Institute for Science
Sponsor: Allan C SpradlingAmplification of Drosophila chorion genes


University of California, San Francisco
Sponsor: Cynthia KenyonAre protein aggregation and aging related


Harvard University
Sponsor: Catherine DulacCharacterizing the thermoregulatory circuits that control animal behavior


Carlsberg Laboratories, Denmark
Sponsor: H HolterGenetic transformations in yeast


California Institute of Technology
Sponsor: David J AndersonA genetic approach to the logic and evolution of aggression circuitry


Yale University
Sponsor: Scott StrobelAbiotic model for tRNA mediated polypeptide synthesis


Harvard University
Sponsor: Mark PtashneCrystallographic study of bacteriophage repressors


Princeton University
Sponsor: Bonnie BasslerManipulating pseudomonas aeruginosa quorum-sensing to control pathogenicity


University of California, Berkeley
Sponsor: Gerald M Rubin

Massachusetts Institute of Technology
Sponsor: Christopher BurgeRole of splicing regulatory factors in co-regulated transcription and splicing


Harvard University Medical School
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University of Wisconsin, Madison
Sponsor: Barry GanetzkyMolecular mechanisms of neurodegeneration


Harvard University
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University of California, Berkeley
Sponsor: Gerald M RubinDrosophila photoreceptor differentiation


University of California, San Francisco
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Harvard University
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Yale University
Sponsor: Lynn CooleyCYSPID: a database of properties and relationships among cytoskeletal proteins on the World Wide Web


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Sponsor: I R LehmanIdentification and purification of deoxyribonucleases of E. coli


Johns Hopkins University
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Brandeis University
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University of California, San Francisco
Sponsor: Wendell A LimControlling the flow of intracellular information: understanding the role of scaffolding proteins in signaling


Rockefeller University
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Massachusetts Institute of Technology
Sponsor: Malcom L Gefter & Jonathan G SeidmanIn vitro splicing of adenovirus 2 mRNA


University of Chicago
Sponsor: Susan L LindquistFunction characterization of the DnaJ protein


University of California, Los Angeles
Sponsor: Steven JacobsenMechanisms of Arabidopsis MORC homologues


University of California, San Francisco
Sponsor: William J RutterCyclic AMP in transcription of eukaryotes


MRC Center, University Medical School, England
Sponsor: Aaron KlugStructure of eukaryotic chromosomes


University of California, Berkeley
Sponsor: Randy SchekmanBiochemical characterization of yeast


Stanford University
Sponsor: Paul BergRegulation of expression of SV40 late genes


University of California, Los Angeles
Sponsor: S Lawrence ZipurskySpecificity of neuronal wiring in Drosophila


University of Utah School of Medicine
Sponsor: Alejandro S AlvaradoTissue homeostasis in planarians


University of Wisconsin, Madison
Sponsor: Harold RuschGenetic control of mitotic cycle


University of Amsterdam, Netherlands
Sponsor: E C SlaterIntermediary metabolism


Stanford University
Sponsor: Jeffrey AxelrodSystem biology approach to dissecting a hierarchical signaling network


University of California, San Francisco
Sponsor: Keith MostovMolecular mechanism of injury repair in 3D epithelia


Harvard University Medical School
Sponsor: Li-Huei TsaiIdentification of a Cdk5 inhibitor in neurogenesis


Harvard University Medical School
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University of California, San Francisco
Sponsor: Peter WalterMechanism of regulation of mitochondrial abundance


Washington State University
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University of California, San Francisco
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Harvard University
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Harvard University
Sponsor: Erin O'SheaDiscovery of commonly prescribed drug gene targets using haploid human cell genetics

National Institute for Medical Research, England
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National Institute for Medical Research, England
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Whitehead Institute for Biomedical Research
Sponsor: Peter S KimCT-CBH1 and its carbohydrate binding properties


California Institute of Technology
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University of California, Berkeley
Sponsor: Iswar HariharanIdentifying proteins involved in cell growth and division


University of Wisconsin, Madison
Sponsor: Millard SusmanBacteriophage maturation


University of California, San Francisco
Sponsor: Ronald O Vale, Ronald D ValeThe kinesin mechanism: two heads and two directions


Karolinska Institutet, Stockholm
Sponsor: Peter ReichardRibonucleotide reductase in regulation and synthesis of deoxyribonuclease


Yale University
Sponsor: Frank SlackQuantitative longitudinal analysis of aging C. elegans populations


Memorial Sloan-Kettering Cancer Center
Sponsor: F Ulrich HartlInteraction of oncogene products with molecular chaperones


Harvard University Medical School
Sponsor: Pamela Silver & Timothy MitchisonMobility and maintenance of a carbon-fixing microcompartment: bioengineering applications and insights into broad mechanisms of bacterial spatial organization


Columbia University
Sponsor: Rafael YusteBehavioral function of pattern completion in the cortex


University of Oregon
Sponsor: Peter H von HippelA role for unstructured, polymeric domains in increasing the kinetics of specific macronuclear association


Princeton University
Sponsor: Abraham WorcelStructure, replication and transcription of folded chromosomes


Harvard University Medical School
Sponsor: Robert G KolterSynthesis of an intracellular starvation signal in E coli


University of Illinois at Urbana-Champaign
Sponsor: Wilfred van der DonkMechanistic studies of lypoxygenase and cylooxygenase


Wistar Institute
Sponsor: A F GrahamReplication of reoviruses


Carnegie Mellon University
Sponsor: Elizabeth W. Jones & Karl DrlicaPhage DNA encapsulation


University College, England
Sponsor: Martin C RaffSchwann cells in peripheral nervous systems interactions


Rockefeller University
Sponsor: Robert G RoederGrowth factor regulation of transcription studied in vitro


University of California, Santa Cruz
Sponsor: Manuel AresThe impact of RNA polymerase II pausing on co-transcriptional splicing


Scripps Research Institute
Sponsor: Peter E WrightNMR studies of the phosphoCREB-CBP interaction

University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center
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Harvard University
Sponsor: Matthew MeselsonDNA in genetic recombination


Boston Children's Hospital
Sponsor: Jonathan KaganMechanisms of transport for bacterial molecules across phagosomal membranes


Fred Hutchinson Cancer Center
Sponsor: Mark GroudineChromatin conformation at the human beta-globin locus


Yale University
Sponsor: R E HandschumacherRegulation of purines and pyrimidines


Stanford University
Sponsor: David S. HognessGenetics of eukaryotic DNA


Harvard University Medical School
Sponsor: Marc W KirschnerThe surface contraction waves of Xenopus eggs reflect cell cycle state


Salk Institute for Biological Studies
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University of California, Los Angeles
Interactions between sensory neurons and skin, with Alvaro


University of Pennsylvania
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Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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Massachusetts Institute of Technology
Sponsor: Dennis KimGenetic analysis of innate immunity in C elegans


California Institute of Technology
Sponsor: Angelike StathopoulosSpatial regulation of the NF-kappaB pathway in Drosophila embryogenesis


University of Geneva, Switzerland


University of Geneva, Switzerland
Sponsor: Harvey Eisen & Paul Patterson, E. FurshpanBinding of bacteriophage lambda with host DNA


Massachusetts Institute of Technology
Sponsor: Herman Eisen & Claude A VilleeFetal cell surface antigens of BALB/c mice


Harvard University Medical School
Sponsor: Melvin V SimpsonMechanisms of RNA interaction in protein synthesis


University of California, San Francisco
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Harvard University Medical School
Sponsor: Bernardo SabatiniThe neural substrate of learned habits


University of California, San Francisco
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New York University
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University of Washington, Seattle
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Harvard University Medical School
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Rockefeller University
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Weill Medical College of Cornell University
Sponsor: Olga BoudkerConformational changes of the glutamate transporter accompanying the release of ligands to the cytoplasm


Stanford University
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Pasadena Foundation for Medical Research
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University of Indiana
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Harvard University
Sponsor: Mark PtashneMolecular mechanisms of TATA-independent gene transcription


MRC Center, University Medical School, England
Sponsor: J D Smith & Sydney BrennerGenetic analysis of developmental pathways in c. elegans


University of Basel, Switzerland
Sponsor: Gottfried Schatzcytoplasmically-synthesized mitochondrial proteins


Rockefeller University
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University of California, Berkeley
Sponsor: Gerald M RubinRegulation of Drosophila P element transposition and expression


Cold Spring Harbor Laboratory
Sponsor: Gregory J. HannonThe biochemistry of RNAi in epigenetic regulation


University of Uppsala, Sweden
Sponsor: Hans Wigzell & Kendall A SmithRegulation of T-lymphocyte proliferation and differentiation


Whitehead Institute for Biomedical Research
Sponsor: Richard MulliganIdentification of enhancer factors


California Institute of Technology
Sponsor: Elliot MeyerowitzControl of cell proliferation by CLV1


University of Washington
Sponsor: Eugene W NesterAgrobacterium infection of yeast


University of Basel, Switzerland
Sponsor: T ReichsteinBiochemistry of steroid hormones

University of Illinois at Urbana-Champaign
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University of Illinois at Urbana-Champaign
Sponsor: Phillip A NewmarkInvestigating mechanisms underlying nervous system regeneration in the planarian Schmidtea mediterranea


Columbia University
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Harvard University Medical School
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University of Pennsylvania
Sponsor: Meera SundaramAnalysis of PP2A function in C Elegans Ras signaling


Princeton University
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Roche Institute of Molecular Biology
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Rockefeller University
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Rockefeller University
Sponsor: Michael YoungA search for the molecular mechanisms and physiological basis of sleep


University of Basel, Switzerland
Sponsor: Gottfried SchatzCharacterization of mitochondrial protein import


Yale University
Sponsor: Alfred L M BothwellCD59 and tyrosine kinases in human T-cell activation


University of California, Berkeley
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Princeton University
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Rockefeller University
Sponsor: Titia de LangeTelomere deletion though homologus recombination


Washington University in St. Louis
Sponsor: Donald C ShrefflerAnalysis of 2 proteins form the murine H-2 complex


Massachusetts Institute of Technology
Sponsor: Gerald R FinkMolecular genetics of yeast nucleus, pathway of nuclear fusion yeast


Boston Children's Hospital
Sponsor: Michael E GreenbergRole of Foxhead foxo3a in longevity and tumorigenesis


Carnegie Institute for Science
Sponsor: Joseph G GallChromosome organization of amphibian oocytes during the lampbrush stage


Memorial Sloan-Kettering Cancer Center
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Rockefeller University
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California Institute of Technology
Sponsor: Sarkis MazmanianThe contribution of the intestinal microbiota to development of colon cancer


Rockefeller University
Sponsor: Gunter BlobelCharacterization of the yeast nuclear pore complex


University of California, San Francisco
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University of California, Berkeley
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Harvard University
Sponsor: Sunny XieRole of nuclear organization in gene regulation


University of California, San Francisco
Sponsor: Wendell LimEngineering novel allosteric control over synthetic T cell receptors to improve cancer immunotherapy


Sidney Farber Cancer Institute
Sponsor: David M LivingstonNucleic acid protein interactions in SV40 T antigens


Michael Reese Hospital, Chicago
Sponsor: Rachmeil LevineIntermediary metabolism


Massachusetts Institute of Technology
Sponsor: Mary Lou PardueSynthesis of histone mRNA on the lampbrush chromosomes of Triturus oocytes by in situ hybridization


Harvard University Medical School


Stanford University
Sponsor: Harden M McConnellNMR and molecular genetics of antibody structure


Duke University
Sponsor: Bruce A SullengerEffect of gene position on ribozyme substrate choice


University of Sussex, England
Sponsor: Paul M NurseControl of mitosis in fission yeast


University of California, San Diego
Sponsor: Michael G RosenfeldDevelopmental regulation of neuroendocrine gene expression


Weizmann Institute of Science, Israel
Sponsor: Leo SachsFiber fractionation


Massachusetts General Hospital
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Harvard University Medical School
Sponsor: Chao-ting WuNovel roles of ultraconserved elements in genome integrity


Stanford University
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New York University
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National Institutes of Health
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Massachusetts General Hospital
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Stanford University
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New York University
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Harvard University
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Instituto Superiore di Sanita, Italy
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Scripps Research Institute
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Scripps Research Institute
Sponsor: Ardem Partapoutian and Andrew WardMolecular structure and mechanism of Piezo mechanotransduction channels


University of Utah
Sponsor: Raymond WhiteHuman polymorphisms due to genomic rearrangements


University of Oregon


National Institutes of Health
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University of Utah
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Rockefeller University
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Rockefeller University
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University of California, San Francisco
Sponsor: Robert M StroudThymidylate synthase and structure-based drug design


University of Oxford, England
Sponsor: Paul NurseIsolation and characterization of fission yeast cell division cycle mutant


Yale University
Sponsor: Frank H RuddleGene transfer


Princeton University
Sponsor: Thomas E ShenkPhysical aspects of adenovirus (AD) which affect AD gene expression


University of Frankfurt, Germany
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Harvard University
Sponsor: Gregory L VerdineUnderstanding the molecular basis of 8-oxo-G repair


Harvard University
Sponsor: Peng YinIntelligent drug delivery by dynamic nucleic acid nano-devices

Imperial Cancer Research Fund Laboratories, England
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Imperial Cancer Research Fund Laboratories, England
Sponsor: John CairnsReplication of herpes virus in isolated nuclei


Stanford University
Sponsor: Robert T SchimkeMechanisms of amplification of folate reductase genes


Yale University
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University of California, San Francisco
Sponsor: Adam Frost and Jonathan WeissmanCharacterization of the endoplasmic reticulum membrane protein complex


University of California, Berkeley
Sponsor: Rebecca HealdThe role of organelle-microtubule linker proteins in the spatial organization of the cell

Walter and Eliza Hall Institute of Medical Research, Australia
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Walter and Eliza Hall Institute of Medical Research, Australia
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Whitehead Institute for Biomedical Research
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California Institute of Technology
Sponsor: Norman DavidsonStructure of attachment site of lambda phage n the bacterial chromosome


Princeton University
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University of California, Irvine
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University of Wisconsin
Sponsor: Harold C Rusch & Albert ClaudeEnzymatic studies of nucleic acids


Carnegie Institute for Science
Sponsor: Allan C SpradlingRegulation of developmental arrest in oogenesis


Rockefeller University
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Rockefeller University
Characterizing the activation of YAP kinase by v-Src


Harvard University
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Fred Hutchinson Cancer Center
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Yale University
Sponsor: Paul GreengardCyclic nucleotides and synaptic transmission


Columbia University
Sponsor: Richard AxelDevelopment of optogenetic tools to probe the formation of social memory


Columbia University
Sponsor: Samuel GraffNucleic acid metabolism


University of Oxford, England
Sponsor: Henry Harris

Weizmann Institute of Science, Israel
Sponsor: Israel Pecht & Zelig EshharRegulation of IgE production by feeR bearing lymphocytes


Harvard University
Sponsor: Erin K. O'SheaRegulation of ribosomal protein gene expression


Whitehead Institute for Biomedical Research
Sponsor: Peter W. ReddienStem cell potential and regulation in planarian regeneration


Yale University
Sponsor: Henry G MautnerMechanism of action of acetylcholine


University of Oxford, England
Sponsor: James L. GowansIn vitro and in vivo studies of mechanism of tolerance induction


University of California, San Francisco
Sponsor: Gordon M TomkinsGene transcription


University of Cincinnati
Sponsor: Peter J StambrookConstruction of an experimental neurocristopathy


Institut de Chimie Biologique, France
Sponsor: Pierre ChambonHormonal regulation of transcription of a gene


Stanford University
Sponsor: David KornIsolation and characterization of DNA polymerases


University of California, Berkeley
Sponsor: Corey S GoodmanCell recognition during neuronal development


Stanford University
Sponsor: R L BaldwinMagnetic resonance of ribonuclease folding


University of Oregon
Sponsor: Vicki L ChandlerElements involved in tissue-specific gene expression


Harvard University Medical School
Sponsor: Johannes WalterMechanism of incision-independent interstrand cross-link repair


University of California, Berkeley
Sponsor: Gerald M RubinCell fate specification in Drosophila eye development


Carnegie Institute for Science
Sponsor: Donald C BrownDifferential regulation of 5S rRNA genes in Xenopus


Rockefeller University
Sponsor: Seth A DarstStructural studies of RNA polymerase using mutants


Columbia University
Sponsor: Richard AxelSensory coding in the vomeronasal pathway


Harvard University
Sponsor: John Chant and Rom A Rapoport, John Chant & Tom A RapoportRe-export of proteins of the endoplasmic reticulum membrane into the cytosol


Albert Einstein College of Medicine
Sponsor: Julius MarmurMechanisms of mitochondrial replication


Institut Pasteur, France
Sponsor: Francois Jacob & Jonathan R BeckwithRegulation of growth; regulation of DNA synthesis in E. coli


Harvard University
Sponsor: John L RinnStructure and function of large non-coding RNAs regulated by p53


Massachusetts Institute of Technology
Sponsor: Bradley BernsteinEpigenetic events in cancer


Columbia University
Sponsor: James E RothmanRegulation of exocytosis


University of California, Berkeley
Sponsor: Andrew DillinDefining the protective role of the mitochondrial stress response in aging


Cleveland Clinic Foundation
Sponsor: Stanley HazenEosinophils, DNA damage and breast cancer


Harvard University
Sponsor: Philip LederMolecular analysis of chromosomal imprinting in mice


Stanford University
Sponsor: Paul BergNature of SV40-induced T antigen


University of California, San Francisco
Sponsor: Ronald ValeBiochemical analysis of mRNA localization in yeast

University of Colorado, Anschutz Medical Campus
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University of Colorado, Anschutz Medical Campus
Sponsor: Jeffrey KieftStructural Basis for Noncanonical Translation Initiation in Viruses


University of Oregon
Sponsor: Brian W MatthewsCrystallographic studies of the BirA protein

National Institute for Medical Research, England
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National Institute for Medical Research, England
Sponsor: Richard FlavellMolecular mechanisms in the B-thelassemias


Harvard University Medical School
Sponsor: Joan V RudermanActivation of cdc 2/cyclin kinase during meiosis in the surf clam


Oklahoma Medical Research Foundation
Sponsor: Joan Conaway & Ronald ConawayRole of phosphorylation in eukaryotic mRNA synthesis


Princeton University
Sponsor: Shirley M TilghmanMelanocyte development in mice


Yale University
Sponsor: Ira MellmanMultivesicular bodies in dendritic cell function


MRC Center, University Medical School, England
Sponsor: Kim A NasmythStructure and regulation of yeast mating-type genes


Frederick Cancer Research Facility
Sponsor: Thomas J SilhavyPhage and bacterial regulatory mechanisms


Harvard University
Sponsor: Guido GuidottiMaltose and maltodextrin transport in E. coli


Stanford University
Sponsor: Laurence KedesPurification and characterization of mRNA coding for myeloma patients


Columbia University
Sponsor: Eric KandelMolecular mechanism of synapse specific targeting of EF1-a and its role in synaptic growth


Carnegie Institute for Science
Sponsor: Allan SpradlingMetabolic transitions during Drosophila oogenesis


University of Wisconsin
Sponsor: W.S. ReznikoffThe interaction of promoters and transcription factors


Max-Planck Institute
Sponsor: C Nusslein-Volhard & Y N JanRNA localization in Drosophila development


University of Cologne, Germany
Sponsor: Klaus RajewskyIdiotype regulation of the immune response


Institut Pasteur, France
Sponsor: Francois JacobOperon expression and lysogeny


Harvard University
Sponsor: Jonathan R BeckwithPeriplasmic protein secretion in E. coli


Stanford University
Sponsor: Thomas ClandininNeural integration of visual information in the Drosophila brain


New York University
Sponsor: Severo OchoaProtein synthesis in Artemia salina


University of Edinburgh, Scotland
Sponsor: John G. ScaifeBiochemistry and genetic characterization of certain E. coli mutants


National Institutes of Health
Sponsor: Malcolm MartinTranslation of SV40 messenger RNA


Harvard University Medical School
Sponsor: Welcome BenderTrans-regulation by the Drosophila bithorax complex


Yale University
Sponsor: Thomas A SteitzStructural study of cotranslational translocation


University of California, San Francisco
Sponsor: Stanley B Prusiner & Patrick BrownA novel method for mutagenesis of a cloned gene


Massachusetts Institute of Technology
Sponsor: Phillip A SharpMammalian transcriptional regulatory proteins and their genes

Johns Hopkins University School of Medicine
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Johns Hopkins University School of Medicine
Sponsor: Rachel GreenDefining mechanisms for selective translation in ribosomopathies


Yale University
Sponsor: Donald M CrothersUnderstanding the DNA recognition and cleavage characteristics of Phenanthrenequinone Dilimine complexes of Thodium (III)


University of California, Berkeley
Factor controlling RNA chain initiation in lambda


University of Arizona
Sponsor: Koen VisscherA single-molecule study of co-translational protein folding


Massachusetts Institute of Technology
Sponsor: Paul R. GrossMechanism of messenger RNA transport from the nucleus to the cytoplasm of the cleaving sear urchin embryo


Purdue University
Sponsor: Michael G RossmannX-ray crystal structure of rhinovirus/antibody and receptor protein complexes


University of North Carolina
Sponsor: Charles W Carter, JrStructural studies of intermediate state hemoglobins


Boston Children's Hospital
Sponsor: Stuart OrkinDNA elements within BCL11A and its target sequences in globin switching


Institute for Cancer Research
Sponsor: Melvin BosmaExpression of immunoglobulin variable region genes in T cells


California Institute of Technology
Sponsor: Frances ArnoldModeling the cytochrome P450 enzyme superfamily

International Laboratory of Genetics and Biophysics, Italy
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International Laboratory of Genetics and Biophysics, Italy
Sponsor: GP Tochini-Valentinin and F GrosMechanism of RN synthesis by RNA polymerase


Yale University
Sponsor: HSN GreeneLiver fractions with glycogenolytic properties


Brandeis University
Sponsor: Nicolaus GrigorieffElectron microscopy of a voltage-gated ion channel


Yale University
Sponsor: Joan A SteitzSignals for RNA splicing


University of California, San Francisco
Sponsor: Stephen M HedrickProtein kinase C in thymocyte selection


Institut Pasteur, France
Sponsor: Charles EpsteinCell division in E. coli


Stanford University
Sponsor: Charles YanofskyNucleic acids in protein synthesis


Massachusetts General Hospital
Sponsor: Robert E KingstonStructural studies of chromatin modifier-PRC1


University of Pennsylvania
Sponsor: John M BuchananPurine metabolism


University of Chicago
Sponsor: Edwin Ferguson and Joseph PiccarilliTGF-B signalling in C elegans development, RNA biochemistry


University of California, San Francisco
Sponsor: Harold E VarmusRegulation of the yeast heat shock transcription factor


Rockefeller University
Sponsor: Leslie VosshallMotivation in the female mosquito


University of Buffalo
Sponsor: Fred M SnellMembrane permeability


University of Colorado, Boulder
Sponsor: David PrescottGenetic organization of DNA


University of Michigan
Sponsor: Vincent MasseyEnzymatic mechanism of molecular oxygen activation


Carlsbadt Laboratorium
Sponsor: K Linderstrom-LangInvestigations toward elucidating the structure of the enzymatically active core of ribonuclease


University of California, Santa Cruz
Sponsor: Harry F NollerStructural studies of ribosomal translocation


Stanford University School of Medicine
Sponsor: W James NelsonBiogeneisi of epithelial cell polarity: the SEC 6/8 complex


National Research Consiglio, Italy
Sponsor: G P Tocchini-Valenti and R SagerPurification of an SV40 DNA replicating system


University of Utah


Yale University
Sponsor: Efriam RackerMetabolism of glucose

Whitehead Institute for Biomedical Research
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Whitehead Institute for Biomedical Research
Sponsor: Peter ReddienIdentification of genetic constituents of learning in songbirds through a new system for molecular marker development


Harvard University Medical School
Sponsor: Stephen LiberlesUnderstanding gut-to-brain signaling through the vagus nerve


Dana-Farber Cancer Institute
Sponsor: Bruce M SpiegelmanControl of mitochondrial function by PGC-1


Memorial Sloan-Kettering Cancer Center
Sponsor: James E RothmanIsolation and characterization of the SNAP receptor


University of California, San Francisco
Sponsor: Peter WalterActivation signals of the unfolded protein response


Whitehead Institute for Biomedical Research
Sponsor: David BaltimoreMolecular basis of antibody complementarity


Johns Hopkins University
Sponsor: Ru Chuh Huang and J Michael BishopGenetric regulation of RNA tumor virus

National Institute of Dental Research and National Cancer Institute
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National Institute of Dental Research and National Cancer Institute
Sponsor: George R Martin & Mark E Sobel and Lance A LiottaReversal of phenotype of transformed fibroblasts


University of California, Berkeley
Sponsor: Andrew DillinCell non-autonomous modulation of electron transport chain-mediated lifespan extension


University of Wisconsin, Madison
Sponsor: David A BrowRNA dynamics in the spliceosome assembly cycle


MRC Center, University Medical School, England
Sponsor: David BlowX-ray diffraction

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Francis CrickSequencing of tRNA


University of California, San Francisco
Sponsor: Ira HerskowitzRegulation of HO gene of S. cerevisiae


Stanford University
Sponsor: Kang ShenMolecular mechanisms of presynaptic assembly and maintenance in D. elegans neurons

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Kim NasmythTransciptional regulation of yeast HO Gene


University of Colorado, Boulder
Sponsor: David HirshDNA replication and transformation in C elegans


University of Cambridge, England
Sponsor: Max Perutz

University of Glasgow, Scotland
Sponsor: D H R BartonBiogenic aspects of phenol oxidation


Cornell University
Sponsor: Hans D VanEttenGene control elements in P450 pisatin detoxification


University of California, Berkeley
Sponsor: John KuriyanThe molecular mechanism of CaMKII activation by specific calcium-spike frequencies


Rockefeller University
Sponsor: Edward ReichMembrane proteins

Harvard University Medical School
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Harvard University Medical School
Sponsor: George ChurchDevelopment of integrated genomic maps

University of California, San Francisco
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University of California, San Francisco
Sponsor: Alexander D JohnsonHost-pathogen interactions of Candida and Drosophila


MRC Center, University Medical School, England
Sponsor: Stanley BrennerExpression of yeast and nematode genes in yeast cells


University of Michigan
Sponsor: Lois WeismanElucidating mechanistic defects associated with dysregulation of a phosphatidylinositol signaling liquid


Massachusetts Institute of Technology
Sponsor: Angelika AmonMolecular basis of karyotype evolution in Ewing's sarcoma


Stanford University
Sponsor: Paul BergSV40 in non-permissive cells


Harvard University School of Public Health
Sponsor: Laurie GlimcherRegulation of the c-Maf protooncogene, a Th2-specific transcription factor


Cold Spring Harbor Laboratory
Sponsor: Nichols K TonksProtein tyrosine phosphatases in PC12 differentiation


Cold Spring Harbor Laboratory
Sponsor: Joseph Sambrook and Sydney BrennerVertebrate embryology


Karolinska Institutet, Stockholm
Sponsor: G BertaniInteractions between the temperate phage P2 and its host cell, E coli


Harvard University Medical School
Sponsor: Christopher T WalshBiosynthetic mechanism of yerisniabactin from Yersinis pestis


Scripps Research Institute
Sponsor: Richard A LernerMoloney murine leukemia virus


Salk Institute for Biological Studies
Sponsor: Melvin CohnMechanisms of biological regulation


Massachusetts Institute of Technology
Sponsor: Barbara ImperialiInterrogating macromolecular interactions at biological membranes


Duke University
Sponsor: Robert L HillStructural characterization of mammlian alpha 1, 3-fucosyl-tranferases


University of California, San Francisco
Sponsor: Cynthia KenyonMi9-13 and cell migration


National Institutes of Health
Sponsor: Harold Stewart

New York University
Sponsor: Severo OchoaSecondary structure on the messenger function of synthetic polyribonucleotides in protein synthesis


University of Colorado, Boulder
Sponsor: Thomas R CechRNA folding in the tetrahymena group 1 intron


Harvard University
Sponsor: Douglas A MeltonControl of early development in Xenopus laevis


Stanford University
Sponsor: Richard TsienOptogenetic deconstruction of local calcium signaling domains


Massachusetts Institute of Technology
Sponsor: Graham C WalkerVitamin B12 in rhizobium-legume symbiosis


National Institutes of Health
Sponsor: B L HoreckerNucleic acid synthesis


University of California, San Francisco
Sponsor: Ronald ValeASH1 mRNA localization in S. cervisiae


University of Oregon
Sponsor: Charles B KimmelMolecular analysis of the zebrafish axial patterning gene floating head


University of Colorado, Boulder
Sponsor: Matthew P ScottTrans-acting regulators of homeotic gene function


University of California, Berkeley
Sponsor: Douglas KoshlandA genomic study of homologous recombination between repetitive elements


Boston Children's Hospital
Sponsor: Jonathan KaganDissecting early host endotoxin sensing mechanisms


Dana-Farber Cancer Institute
Sponsor: William G Kaelin, JrNovel genetic approaches in the study of tumor suppressor VHL


California Institute of Technology
Sponsor: William ClemonsA key to the discovery of new antibacterials: structure determination of an essential bacterial membrane protein, MraY


Harvard University
Sponsor: David LiuDevelopment of smart genome-editing agents for targeted therapy


Stanford University
Sponsor: Ronald LevyA novel vaccine for B-cell lymphoma


University of Oxford, England
Sponsor: H A KrebsFactors controlling metabolism at the cellular and sub-cellular level


University of Washington
Sponsor: Willam N ZagottaImaging dynamics in CNG ion channels

McGill-Montreal General Hospital Research Institute
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McGill-Montreal General Hospital Research Institute
Sponsor: J.H. QuastelTumour viruses


University of Cambridge, England
Sponsor: L E OrgelMechanism of action of the hemoprotein enzymes


Stanford University
Sponsor: Robert SchimkeCharacterization of polyribosome-membrane interaction

MRC Center, University Medical School, England
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MRC Center, University Medical School, England
Sponsor: Aaron KlugStructure of vertebrate striated muscle


Whitehead Institute for Biomedical Research
Sponsor: Gerald R FinkTransport of ribosomal proteins to the yeast nucleus


Massachusetts Institute of Technology
Sponsor: U L RajBhandaryControl of differentiation and development in eukaryotes


University of California, Berkeley
Sponsor: Robert TjianBookmarking the chromosomes and its role in cellular memory


Rockefeller University
Sponsor: Keith R PorterElectron microscopic study of the mammary tumer inciter


Massachusetts Institute of Technology
Sponsor: Robert G GriffinSolild state NMR studies of bacteriorhodopsin


Carnegie Institute for Science
Mechanism of cell-specific transcriptional activation


Stanford University
Sponsor: I. R. LehmanDNA Polymerase


University of Uppsala, Sweden
Sponsor: Lennart PhilipsonGenome structure of adenovirus


National Institutes of Health
Sponsor: Philip LederTranscription control of globin synthesis


New York University
Sponsor: Severo OchoaMetabolism of propionic acid in animal tissure


University of Washington
Sponsor: Leland HartwellMating partner selection in yeast


California Institute of Technology
Sponsor: Howard D LipshitzRNA and protein localization in the Drosophila egg


Karolinska Institutet, Stockholm
Sponsor: Hans WigzellRole of antigen binding receptor onlumphocytes in intolerance and immunity


University Medical School, England
Sponsor: Sydney BrennerBiochemistry of cells as controlled by genetic units


New York University
Sponsor: Ruth LehmannmRNA stability during Drosophila germline


University of California, Berkeley
Sponsor: Gerald R RubinTargets of glas in the Drosophila eye disc


Yale University
Sponsor: William U GardnerEndocrine aspects of mammary gland growth and function


Yale University
Sponsor: Ari HeleniusRole of lectins in glycoprotein


Boston Children's Hospital
Sponsor: Leonard ZonThe role of prostaglandins and Wnt signaling on hemopoietic stem cell renewal


Salk Institute for Biological Studies
Sponsor: Robert W HolleyCell differentiation


University of Chicago
Sponsor: Susan LindquistEffect of [PSI+] on gene expression


Sidney Farber Cancer Center
Sponsor: Jack L StromingerEarly antigen complex of EB virus


National Cancer Institute
Sponsor: Susan GottesmanBacterial cell cycle


California Institute of Technology
Sponsor: Richard DickersonProtein structure


Memorial Sloan-Kettering Cancer Center
Sponsor: Scott LoweThe role of ribosomal protein gene deletions in liver cancer


Whitehead Institute for Biomedical Research
Sponsor: Gerald R FinkQuorum sensing in fungi


University of Colorado, Boulder
Sponsor: Olke Uhlenbeck, Olke UlenbeckEnzymology of the DEAD family of RNA dependent ATPases


Massachusetts General Hospital
Sponsor: Jane B Lian and Jerome GrossVitamin K in normal and neoplastic bone formation


Princeton University
Sponsor: Thomas ShenkMolecular interactions of YY1


California Institute of Technology
Sponsor: Gilles LaurentcAMP and sensory representations in the mushroom body


Cornell University
Sponsor: R E MacdonaldRibosome synthesis


Cornell University
Sponsor: R E MacDonaldWork on ribosome synthesis


Columbia University
Sponsor: Nicholas J TurroTime-resolved binding studies of Ru complexes to DNA


University of Alberta, Canada
Sponsor: R C von BorstelMolecular basis of DNA repair


Stanford University
Sponsor: Robert L BaldwinMechanism of folding of RNase studies by 2-D NMR


Johns Hopkins University
Sponsor: Saul RosemanIntercellular adhesion


Massachusetts Institute of Technology
Sponsor: Angelika AmonDeciphering the age effects on meiosis and vice versa


Massachusetts Institute of Technology
Sponsor: Herman EisenRole of proteases of macrophages and lymphocytes in immunological reaction


Massachusetts Institute of Technology
Sponsor: JoAnne StubbeMechanistic investigation of ribonucleotide reductases


Tufts University School of Medicine
Sponsor: Ralph R IsbergIntracellular multiplication of legionella


Harvard University
Sponsor: Eric N. Jacobsen

Jackson Laboratory
Sponsor: Roel VerhaakGlioma evolution in the presence of local immune activity


Massachusetts Institute of Technology
Sponsor: David BaltimoreRibonucleic acid synthesis of vesicular stomatitus virus


Carnegie Institute for Science
Sponsor: Donald D BrownThyroid hormone receptors in Xenopus metamorphosis


Stanford University
Sponsor: Paul BergTransformation by altered SV40 genomes


Salk Institute for Biological Studies
Sponsor: Inder M VermaFunction and regulation of the proto-oncogene fos


Massachusetts Institute of Technology
Sponsor: Leonard GuarenteCalorie restriction and aging in C elegans


Harvard University
Sponsor: Douglas A MeltonMolecular response to inductive interactions in vertebrate embryos


Harvard University Medical School
Sponsor: Tom A RapoportElucidation of factors involved in ER network formation


University of Washington
Sponsor: Dan StetsonExploring the connections between antiviral responses and autoimmunity


Harvard University Medical School
Sponsor: Christopher T WalshMechanistic studies of epothilone biosynthesis


Columbia University
Sponsor: Gary StruhlPlanar cell polarity protein activity and function in developing Drosophila epithelia


Harvard University
Sponsor: Richard Losick & Roberto KolterDissecting the molecular basis of mutually beneficial interactions between plants and bacteria


New York University
Sponsor: Ochoa, SeveroEnzyme systems that synthesize nucleic acids


Duke University
Sponsor: Michael P SheetzCell cycle regualtion of cytoplasmic dynein


Yale University
Sponsor: Harry S.N. GreeneComparing the growth of tumors in such media to those transplanted in the anterior chamber


Harvard University Medical School
Sponsor: Elkan R Blout and Richard HendersonMembrane protein and peptides


Johns Hopkins University
Sponsor: M A Naughton and H M DintzisProtein biochemistry and structure


Rockefeller University
Sponsor: C. David AllisFunctional and mechanistic study of histone crotonylation in leukemiaÂ’s


University of California, San Francisco
Sponsor: Ronald ValeMechanisms of mitotic spindle positioning by cortical dynein


Harvard University
Sponsor: Xiaowei ZhuangImaging protein translation at the single-molecule level in living cells


Massachusetts Institute of Technology
Sponsor: Michael LaubProbing the role of peptidoglycan in establishing bacterial cell polarity


University of California, San Diego
Sponsor: Yishi JinCharacterization of new axon regeneration regulation pathways


Harvard University
Sponsor: Xiaowei ZhuangChromatin imaging with STORM-FRET labels


Massachusetts Institute of Technology
Sponsor: David BaltimoreCharacterzation of the A-MuLV transforming genotype


University of Glasgow, Scotland
Sponsor: J K GrantBiosynthesis of adrenocortical sterioids


Max-Planck Institute
Sponsor: Peter H HofschneiderGene order and translational reguation of the phage M12


University of California, San Francisco
Sponsor: Marc W KirshnerMechanism of action of maturation promoting factor


Massachusetts Institute of Technology
Sponsor: Boris MagasanikIntracellular metabolic control


Duke University
Sponsor: Lorena BeeseStructural Biology of human mismatch repair

University of North Carolina, Chapel Hill
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University of North Carolina, Chapel Hill
Sponsor: Edward D SalmonInteractions of microtubules and actin in cell motility


University of Edinburgh, Scotland
Sponsor: Andrew H WyllieAnalysis of apoptosis using a cell-free assay


Harvard University Medical School
Sponsor: Paul H PattersonGlial factor controlling neruoblasts differentiation


Massachusetts Institute of Technology
Sponsor: Alexander RichDNA Replication

University of California, Berkeley
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University of California, Berkeley
Sponsor: Carlos BustamanteRNA, ribosome and RNA polymerase: three molecules at a time


University of Colorado, Boulder
Sponsor: Thomas R CechMechanisms of protein facilitated RNA catalysis


University of Texas Southwestern Medical Center
Sponsor: Gaudenz DanuserBleb-nucleated signaling scaffolds in metastasis-prone melanoma cells


University of California, Davis
Sponsor: John L IngrahamStructure and assembly of bacterial ribosomes


Massachusetts Institute of Technology
Sponsor: Angelika AmonAneuploidy effect on protein homeostasis


Salk Institute for Biological Studies
Sponsor: Melvin CohnGenetic mechansims that control the production and specificity of antibodies


University of Washington, Seattle
Sponsor: Leland H HartwellMolecular analysis of cdc15 in chromosome segregation


Harvard University Medical School
Sponsor: Sandeep DattaUnified model of social processing in prefrontal cortex


Stanford University
Sponsor: I R LehmanIn vitro replication of col E1 DNA


University of California, San Francisco
Sponsor: Thomas KornbergEffect of protein synthesis inhibition on transcript localization


University of California, Berkeley
Sponsor: Daniel E Koshland, Jr.Adaptiation of E. Coli and S. typhimurium to chemostatic stimuli


Brandeis University
Sponsor: Carolyn CohenStructure of fibrinogen


MRC Center, University Medical School, England
Sponsor: F SangerSequence analysis of high molecular weight RNA from oncongenic viruses


University of California, Berkeley
Sponsor: Alan SachsPoly(A)-dependent control of translation initiation

University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center
Sponsor: Michael S BrownSterol repressor: genetic and biochemical analysis


University of California, San Francisco
Sponsor: Cori BargmannSpecificity in G protein signal transduction


University of Medicine and Dentristry New Jersey
Sponsor: Ann M StockActivation of a bacterial signal transduction protein


Harvard University Medical School
Sponsor: Charles A Thomas, Jr & Thomas W SneiderDNA transmethylation


University of Michigan
Sponsor: H N ChristensenTransport systems and amiono acid transport


Yale University
Sponsor: Alan GarenEmbryonic determination and differentiation in Drosophila


Stanford University
Sponsor: David S HognessDNA structure of Drosophila


Princeton University
Sponsor: James E RothmanRole of NSF attachment protein in Golgi transport


Harvard University Medical School
Sponsor: John MekalanosIdentifying novel nucleotide second messengers from mammals using bacteria


Harvard University
Sponsor: Douglas A MeltonSignal transduiction mechanisms during neural induction


University of Wisconsin, Madison
Sponsor: Van R PotterNucleic acid metabolism


Wesleyan University
Sponsor: Steven PotterTransposable elements in integrated mammalian systems


University of Chicago
Sponsor: Samule B WeissCellular protein synthesis


MRC Center, University Medical School, England
Sponsor: Aaron KlugHigher order folding in chromatin


California Institute of Technology
Sponsor: John AbelsonsnRNP interactions of the yeast splicing protein, PRP4


University of Wisconsin, Madison
Sponsor: Marvin P WickensPost-transcriptional control of gene expression


Johns Hopkins University
Sponsor: Edward G HeathStructure and composition of core portion of the cell wall lipopolysaccharide of E. coli


University of Colorado, Boulder
Sponsor: Thomas R CechPreparing active subsystems of Tetrahymena ribozyme


Harvard University Medical School


Johns Hopkins University
Sponsor: Howard DintzisProtein chemistry


Stanford University
Sponsor: Peter SarnowIdentification of picornavirus-susceptibility genes


Salk Institute for Biological Studies
Sponsor: Garth NicolsonMechanism of tumor metastasis


University of Hawaii
Sponsor: Tom Humphreys & John WB HersheyTranslational regulation of protein synthesis


Whitehead Institute for Biomedical Research
Sponsor: David BaltimoreImmunoglobulin DNA rearrangement enzyme(s)


Harvard University Medical School
Sponsor: Mario Capecchi & Thomas L BenjaminChain termination in eukaryotes


Johns Hopkins University
Sponsor: Albert L LehningerProperties of mitochondrial membranes


Harvard University
Sponsor: Stuart L SchreiberCombinatorial design of a PH-domain binder


University of California, Berkeley
Sponsor: Peter G SchultzThe generation of new tRNAs to expand the genetic code


Yale University
Sponsor: Arthur L Horwich, Arthur R HorwichRole of the chaperone component of ClpAP protease


Universite de Bruxelles, Belgium
Sponsor: Jean BrachetPhysiology and histochemistry of developing amphibian eggs and embryos


Massachusetts Institute of Technology
Sponsor: H Robert Horvitz & Martin ChalfieEgg-laying constitutive mutants of the nematode C elegans


University of California, Berkeley
Sponsor: Carolyn BertozziDevelopment of an isotopic labeling approach for rapid profiling of the O-glycoproteome


Harvard University Medical School
Sponsor: Philip LederAn inherited limb deformity created by insertional mutagenesis in tg mouse


Albert Einstein College of Medicine
Sponsor: Jerard HurwitzDNA recombination and replication


Carlsberg Laboratorium
Sponsor: K. Linderstrom & Lang & O. WingerEffects of glyceris acid and related metabolites on two mutants requiring serine or glycine


Harvard University Medical School
Sponsor: Tom RapaportProbing the molecular mechanism of ERAD-L


Massachusetts Institute of Technology
Sponsor: P W RobbinsLipopolysaccharides in Salmonella


University of Wisconsin, Madison
Sponsor: Harrison EcholsRegulation of repression of DNA transcription of early genes


Yale University
Sponsor: Paul GreengardRegulatory roles of synaptic phosphoproteins


Carnegie Institute for Science
Sponsor: Joseph G GallIntranuclear organelles that contain snRNPs


Columbia University
Sponsor: Peter ScheiffeleThe contribution of neuroligin and neurixin diversity to synaptic specificity


Rockefeller University
Sponsor: Elaine FuchsCoordinated cytoskeletal dynamics and epidermal polarity: implications in skin cancer


Boston Children's Hospital
Sponsor: Yi ZhangDissecting functions of long noncoding RNAs in cardiac progenitors and heart development


Dana-Farber Cancer Institute
Sponsor: David M LivingstonCloning and characterizing the EIA-binding protein p400


Harvard University Medical School
Sponsor: Angela DePaceConnecting sequence divergence to quantitative phenotype differences in drosophila


Dana-Farber Cancer Institute
Sponsor: William KaelinUnbiased analysis of the mitochondrial permeability transition pore


Yale University
Sponsor: Joan A SteitzsnRNA catlyzed splicing in the absence of proteins


University of California, Berkeley
Sponsor: Bruce Ames & G. SatoRegulation of repression in histidine operon of S. typhimurium


Yale University
Sponsor: Mark B GersteinPredicting membrane Helix interactome


Dana-Farber Cancer Institute
Sponsor: David M LivingstonBiological analysis of intrinsic CBP HAT function


University of California, San Diego
Sponsor: Massimo ScanzianiCircuit analysis of sensory activated neuronal ensembles in mammalian cortex


Stanford University
Sponsor: Dimitri Petrov and David RelmanAdaptation and dispersal in the evolution of microbial communities


National Institutes of Health
Sponsor: William B JakobyMetabolism of compounds with the acetylene bond


University of California, Berkeley
Sponsor: Robert TjianChanges in the core transcriptional machinery during cellular reprogramming


Stanford University
Sponsor: Lubert StryerSignal transduction in vision


University of California, San Francisco
Sponsor: Wendell A LimSynthetic feedback shapes MAPK cascade signaling


Harvard University Medical School
Sponsor: Rachel WilsonInvestigating the role of descending neurons in flexible motor control


University of California, San Francisco
Sponsor: Yuh Nung JanIdentification of neuroprotective genes in Drosophila


Stanford University
Sponsor: Paul BergEnzyme-tRNA interactions


University of California, Berkeley
Sponsor: Kristin ScottSensory integration of taste and smell in drosophila


Massachusetts Institute of Technology
Sponsor: Malcolm L GefterRole of elongation factors in DNA synthesis


Harvard University Medical School
Sponsor: Tom A RapoportFunctional assays and crystallization of TAP


Harvard University Medical School
Sponsor: Stephen J ElledgeFunctional genomic approach for protein turnover regulation


Harvard University Medical School
Sponsor: Marc W KirschnerCell cycle regulators of cyclin degradation


University of California, San Francisco
Sponsor: Ronald D. ValeMolecular engineering of kinesin motors


Harvard University Medical School
Sponsor: Thomas WalzStructural characterization of gene silencing complexes


University of California, San Francisco
Sponsor: David JuliusElucidating thermal gating mechanisms of an ion channel involved in pain


University of California, Berkeley
Sponsor: James Hurley and Roberto ZoncuMechanism of mTORC1 lysosomal recruitment via Rag:Ragulator


University of California, Berkeley
Sponsor: Jasper Rine

California Institute of Technology
Sponsor: Bruce A HayIdentifying regulators of cell death in Drosophila


University of California, Berkeley
Sponsor: Rachel BremGenome-wide identification of regulatory non-coding RNAs in S. cerevisiae


University of Washington
Sponsor: David BakerComputational redesign of cytochrome P450 function and applications to synthetic biology


Rockefeller University
Sponsor: Zanfil A CohnPurification of cytotoxic proteins from lymphocytes


Salk Institute for Biological Studies
Sponsor: Robert W HolleyIsolation of SV3Ts growth factors


Rockefeller University
Sponsor: Leslie VosshallProcessing human cues in the mosquito brain


Harvard University
Sponsor: Richard LosickThe cloning of B subtilis sporulation genes


University of California, San Francisco
Sponsor: Loren FrankInvestigating the mechanism of memory recall

University of California, San Francisco
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University of California, San Francisco
Sponsor: Ronald D. ValeImaging molecular interactions upon ephrin-Eph receptor-mediated adhesion/repulsion responses in live cells


Oxford University, England
Sponsor: E R H JonesIsotopic labelling of various organic substances


Stanford University
Sponsor: Edward I SolomonStructure/function relationships in anticancer activity


University of California, San Francisco
Sponsor: Keith YamamotoGlucocorticoid-inducible DNase sensitivity


Duke University
Sponsor: Bruce A SullengerIn vivo specificity of ribozyme-mediated mRNA repair


University of California, Los Angeles
Sponsor: Lawrence ZipurskyRole of MAP kinase (ERK) in signal transduction


University of Illinois at Urbana-Champaign
Sponsor: Phillip A NewmarkThe molecular basis of neurogenesis in planarians


Brigham and Women's Hospital
Sponsor: Mitzi KurodaAnalysis of dosage compensation in Drosophila


University of California, Berkeley
Sponsor: Daniel ZilbermanComparative genomic analysis of DNA methylation in animals


University of California, Los Angeles
Sponsor: S Lawrence ZipurskyDown syndrome cell adhesion molecule and repulsive axon guidance in Drosophila


Lawrence Berkeley National Laboratory
Sponsor: Carlos BustamanteSingle-molecule study of chromatin remodeling


Stanford University School of Medicine
Sponsor: Matthew P ScottVesicle trafficking in neural development


University of Illinois at Urbana-Champaign
Sponsor: Taekjip HaDetermining the transition of genomic softness in the cancer progression


Columbia University
Sponsor: Charles Zuker & Tom ManiatisFunctional segregation of taste-responsive neurons


New York Genome Center
Sponsor: Rahul SatijaFunctional interactions bewtween the neuronal and immune cells


Massachusetts Institute of Technology
Sponsor: Leonard GuarenteFactors that regulate the activity of the transcriptional activator HAPI


Rockefeller University
Sponsor: Roderick MacKinnonMechanisms of ATP-sensitive potassium, (KATP) channel gating


Stanford University School of Medicine
Sponsor: Matthew P ScottThe roles of Costal2 in hedgehog signaling


Yale University School of Medicine
Sponsor: Ruslan MedzhitovCounter-inflammatory mechanisms in tissue inflammation


University of California, Berkeley
Sponsor: Rebecca HealdUncovering molecular determinants of mitotic chromosome scaling


Massachusetts Institute of Technology
Sponsor: Phillip A SharpHIV-1 TAR-binding proteins in Tat trans-activation


Harvard University
Sponsor: Rachelle GaudetNoxious chemical sensing by the TRPA1 ion channel


University of California, San Francisco
Sponsor: Alexander JohnsonMolecular analysis of bistability in a eukaryotic transcriptional network

Whitehead Institute for Biomedical Research
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Whitehead Institute for Biomedical Research
Sponsor: David SabatiniNot just a recycle bin: the role of lysosomes in nutrient sensing by the mammalian target of rapamycin


Harvard University
Sponsor: Sharad RamanathanUnderstanding decision-making during embryonic stem cell differentiation


Harvard University Medical School
Sponsor: Marc W KirschnerSister chromatid separation in vertebrate cells


Johns Hopkins University School of Medicine
Sponsor: Philip ColeAcetylomics of the leukemia protein MOZ


University of California, Berkeley
Sponsor: Gerald M RubinIsolation and structure of a rhodopsin gene from D. melanogaster


National Institutes of Health
Sponsor: Michael J LenardoThymic differentiation